ID   A0A1M5MDQ4_9ACTN        Unreviewed;      1319 AA.
AC   A0A1M5MDQ4;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:SHG75395.1};
GN   ORFNames=SAMN05444351_3130 {ECO:0000313|EMBL:SHG75395.1};
OS   Geodermatophilus nigrescens.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Geodermatophilus.
OX   NCBI_TaxID=1070870 {ECO:0000313|EMBL:SHG75395.1, ECO:0000313|Proteomes:UP000184471};
RN   [1] {ECO:0000313|EMBL:SHG75395.1, ECO:0000313|Proteomes:UP000184471}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45408 {ECO:0000313|EMBL:SHG75395.1,
RC   ECO:0000313|Proteomes:UP000184471};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FQVX01000003; SHG75395.1; -; Genomic_DNA.
DR   STRING; 1070870.SAMN05444351_3130; -.
DR   OrthoDB; 9805617at2; -.
DR   Proteomes; UP000184471; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR024590; HrpA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010222; RNA_helicase_HrpA.
DR   NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF11898; DUF3418; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:SHG75395.1};
KW   Hydrolase {ECO:0000313|EMBL:SHG75395.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184471}.
FT   DOMAIN          89..252
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          286..452
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   1319 AA;  145127 MW;  5C1B1976BE499D6F CRC64;
     MEPSTAVTAT LPDLRSRLAA LTLEDEHRLG RRLEGLRRTR DAAARERALE RITADVVAAE
     ERIARRRAAV PAVTYPEGLP VSARRDDIAA ALRESQVVVV AGETGSGKTT QLPKIALELG
     RGVRGRIGHT QPRRIAARTV AERIAEELET PLGGAVGWKV RFTDQVGDAT SVKLMTDGVL
     LAEIAHDRLL RQYDTIIVDE AHERSLTIDF LLGYLAQLLP RRPDLKVVIT SATIDVERIA
     KHFGLDGAEV PVVEVSGRTY PVEVRYRPVV DPDDPDADPD RDQVTAIGDA VEELAAEGPG
     DVLVFLAGER EIRDAADVLT ERFPGTEVLP LYSRLSAADQ HRVFQPHTGR RIVLATNVAE
     TSLTVPGIRY VVDPGTARIS RYSARTKVQR LPIEPISQAS ARQRSGRCGR VADGIAIRLY
     TEEDFEGRPE YTDPEILRTS LASVLLQMAA LDLGAVEDFP FVDPPDRRAV TDGRALLEEL
     GALEDGRLTD TGRALAQLPL DPRLGRMVVE ADRRGVLEEV LVIAAGLTIQ DPRERPAEHQ
     QAADQMHARF ADEHSDFLAL LNLWRYLTGQ QDALSGSQFR KTVKREFLHY VRIREWQDLH
     GQLRGTARRL GMTVGALAAE PDERGVSTAL LAGLLSQVGL QLEEKRKDGD RRRGGREYLG
     ARGARFVIAP GTPLARKPPR WVVAAELVET SRLFARTVAR VDPEDVERLA GHLVSREYSE
     PRWDARRGSV VATERVTLYG IPLVVGRRVQ YGSIDPVVSR ELFIRHALVQ GEWTTHHRFW
     ADNQRALERV AELEERARRR DIRVDDETLF ELYDARVPAD VVSTRHFDRW WKTARQRTPD
     LLTLTPEMLT DAAAAGQVRA EDFPDEVPLT QGLTLPLSYA FAPGAPEDGV TVDVPLAVLD
     SVVEQTSGES LAFTVPGLRE ELVTALLRTL PKQLRRALVP IPDRVREVLP RIAPTEPLLP
     ALERELRRAA AVVVPPDAWQ PAQVPGHLRA TFRVVDDRQR ALATGKDLQA LRREVAPQAR
     ASLAAAASDV ERTGLTAWTI GELPRTVEVR RGGHAVTAYP ALVDEGATVG VRVVSTEAEA
     ARLSWRGSRR LLVLVAGSPT RQVVKGLSPR SRLALQFNPD GEIPALVDDC VDAAADELVA
     AAGGPPRDGA AFAALVATAK EQLLPLTQDA VRRVEAVLTQ AREVAVAIGA APGRRVPEAA
     VADLRRQMGG LLHRGFVADA GRRRLPDLVR YLKAMAYRLE KLPANAVRDA LWTDQVAAVT
     AEYEQLRREV PPTGAPDDPV TRIRWMVEEL RVGLFAQQIG TPRPVSEQRL YKAIDALTA
//