ID   A0A1M5NIH1_9FIRM        Unreviewed;       709 AA.
AC   A0A1M5NIH1;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Fe-S oxidoreductase {ECO:0000313|EMBL:SHG89292.1};
GN   ORFNames=SAMN02745221_01211 {ECO:0000313|EMBL:SHG89292.1};
OS   Thermosyntropha lipolytica DSM 11003.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Syntrophomonadaceae;
OC   Thermosyntropha.
OX   NCBI_TaxID=1123382 {ECO:0000313|EMBL:SHG89292.1, ECO:0000313|Proteomes:UP000242329};
RN   [1] {ECO:0000313|Proteomes:UP000242329}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11003 {ECO:0000313|Proteomes:UP000242329};
RA   Varghese N., Submissions S.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FQWY01000017; SHG89292.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1M5NIH1; -.
DR   STRING; 1123382.SAMN02745221_01211; -.
DR   OrthoDB; 5241828at2; -.
DR   Proteomes; UP000242329; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   Gene3D; 1.20.950.20; Transmembrane di-heme cytochromes, Chain C; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR004017; Cys_rich_dom.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR023234; NarG-like_domain.
DR   InterPro; IPR036197; NarG-like_sf.
DR   PANTHER; PTHR43255:SF6; IRON-SULFUR-BINDING OXIDOREDUCTASE FADF-RELATED; 1.
DR   PANTHER; PTHR43255; IRON-SULFUR-BINDING OXIDOREDUCTASE FADF-RELATED-RELATED; 1.
DR   Pfam; PF02754; CCG; 2.
DR   Pfam; PF13183; Fer4_8; 1.
DR   Pfam; PF02665; Nitrate_red_gam; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF103501; Respiratory nitrate reductase 1 gamma chain; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 2.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242329};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        27..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        88..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        127..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        163..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        230..248
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          293..324
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   709 AA;  81662 MW;  2B72C74F85D7AEAE CRC64;
     MIFGYIPLEG GYEVPMRVVG ANIPFEWLIY ILMFIPLGVF IYGFYKRVQV WMLAKGEIHR
     NDKIGQRIWS WFVYTFLQLR LFKKPTPGTM HAFLFWGFLV LFLAAGVDAS HHWLGFPHIE
     GASYIGFSAF VDIFGALALI GIIVLAVIRY VQKPDRLNDT KSSDGWIILL VFAILLTGYF
     IEGARIMAQI KWSTHISEIM YEKYASPVGW YFAFLFQGMS RDAVLMWHRI LWWFHMALAF
     LFIALIPYTK LWHIMTGMLN YIFRNLEPSE IRVIKNIEEA ETFGVEKIEE FGWKDLLDLD
     ACIRCGRCQE NCPAYNTGKH LNPKITLIQH MKQHLDEKAP YLLKQKEQEA DAEMVAMTEE
     AEAVNPMEKS LIYDVVTTDV IWDCTNCRAC MEHCPMFIEH IPKIIEMRRN LVMWQGDMPS
     EAQMAFTNME RNYNPWGVGW ANRAEWLKER GIREMVNVLS EDGGEFEYLL YAGCAVSFDD
     RYKKVGEALV RLLNKAGVSF AYLGTEEMCC GDSARRLGNE YLFQTLAMQN IENFNNYGVK
     KIIVVCPHGY NTIKKEYPQL GGTYEVYHYT EILAKLVAEG KLKPSKVQAV KTTYHDSCFL
     GRHNDVYDEP RQVLKAAGCN IVEIPQTRNK GFCCGAGGGR MWLEEHAVEG YKRINDTRTE
     QLLSPDPEMI VTNCPFCLTM ISDGVKGVNM EEKVKVFDVA EVLWKSIEQ
//