ID A0A1M5QAN5_9EURY Unreviewed; 401 AA.
AC A0A1M5QAN5;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Potassium/proton antiporter membrane subunit, CPA2 family {ECO:0000313|EMBL:SHH11234.1};
GN ORFNames=SAMN05443636_1822 {ECO:0000313|EMBL:SHH11234.1};
OS Halobaculum gomorrense.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halobaculum.
OX NCBI_TaxID=43928 {ECO:0000313|EMBL:SHH11234.1, ECO:0000313|Proteomes:UP000184357};
RN [1] {ECO:0000313|EMBL:SHH11234.1, ECO:0000313|Proteomes:UP000184357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 9297 {ECO:0000313|EMBL:SHH11234.1,
RC ECO:0000313|Proteomes:UP000184357};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. {ECO:0000256|ARBA:ARBA00005551}.
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DR EMBL; FQWV01000004; SHH11234.1; -; Genomic_DNA.
DR RefSeq; WP_073308710.1; NZ_FQWV01000004.1.
DR AlphaFoldDB; A0A1M5QAN5; -.
DR STRING; 43928.SAMN05443636_1822; -.
DR OrthoDB; 12029at2157; -.
DR Proteomes; UP000184357; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR42751:SF4; K(+)_H(+) ANTIPORTER SUBUNIT KHTU; 1.
DR PANTHER; PTHR42751; SODIUM/HYDROGEN EXCHANGER FAMILY/TRKA DOMAIN PROTEIN; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000184357};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 13..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..382
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 401 AA; 40137 MW; 4815445E2DB178E4 CRC64;
MAVGPDAAVV GDLHGLLALG VLIAAATLVA AVGRRVGIPT VPLYVLGGVL VGPHVAGAVG
LPSIAPAEVL TLAEVGVVLL LFFLGLEFSI DRLIDARRKL SAAAAVDLFV NFPVGVALGL
LFGLGPLGAF LVGGIVYISS SAVITKSLVD LGWIADPEAE PVLGTLVAED LVIAVYLALA
VALVAGGSPV DALPRIAVAL GFLIAVAAAA QLLAPRLAPY LGTSDEDLVV RTLAVALVVS
GLALAVGASE AVAGFFVGVG VGATPLHDRV ADRIAPLRDA FAVVFFAWVG LNTDPVAVAG
VAAFVLAAAA LSGPTKVISG AVGGRLYDLS PRRSLRTGLA LVARGEFSLI IAALAATSPD
PTIARVIPAF AVGYVLVMAF AGTLAMSEAD RIERLLGVAD G
//
