ID A0A1M5QZC8_9CLOT Unreviewed; 448 AA.
AC A0A1M5QZC8;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Nucleobase:cation symporter-2, NCS2 family {ECO:0000313|EMBL:SHH19069.1};
GN ORFNames=SAMN02745207_00371 {ECO:0000313|EMBL:SHH19069.1};
OS Clostridium grantii DSM 8605.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1121316 {ECO:0000313|EMBL:SHH19069.1, ECO:0000313|Proteomes:UP000184447};
RN [1] {ECO:0000313|EMBL:SHH19069.1, ECO:0000313|Proteomes:UP000184447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8605 {ECO:0000313|EMBL:SHH19069.1,
RC ECO:0000313|Proteomes:UP000184447};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; FQXM01000002; SHH19069.1; -; Genomic_DNA.
DR RefSeq; WP_073336392.1; NZ_FQXM01000002.1.
DR AlphaFoldDB; A0A1M5QZC8; -.
DR STRING; 1121316.SAMN02745207_00371; -.
DR OrthoDB; 9805749at2; -.
DR Proteomes; UP000184447; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR017588; UacT-like.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; NF037981; NCS2_1; 1.
DR NCBIfam; TIGR03173; pbuX; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000184447};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 448 AA; 46594 MW; B8323DFB7A1AAB29 CRC64;
MSSNQKSLLF QYDGKPSLKE IIPLGLQHVV AMIVGCVTPA LIISGVADLT PADKILLVQA
SLFFAGIATL IQIFPIGKRI GSRLPVIMGV SFAYVPTLVA IAGEFNMATV FGAQIIGGLV
AILFGLFLKK LLVFFPPLVT GTVIFSIGLS LYSVAIKYIA GGVGSATFGS PKNWAVALLT
LGVVLFVNYF TKGSLKLASI LIGIIVGYIV SIFLGMVSFD AVASAGLVQI PKPLHFGIQF
NATAIISMVI MYIVNSVQAI GDLSATTGGG MDRVPTDEEL AGGVIGNGFS SIIGALFGCM
PTATYSQNVG IVTVNKVINK WVFAFASFVV ILAGVVPKFA SLLTTIPQCV LGGATISVFA
TITMTGVKMI ASNNLTMRNS AVVGIAVALG VGIVQVPDAF ALFPSWFISI FGKSSIVVTT
IVAIALNLIL PKDKEIVLSS AKGDSKSV
//
