ID A0A1M5SHS8_9CLOT Unreviewed; 726 AA.
AC A0A1M5SHS8;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Stage V sporulation protein D (Sporulation-specific penicillin-binding protein) {ECO:0000313|EMBL:SHH38104.1};
GN ORFNames=SAMN02745207_00947 {ECO:0000313|EMBL:SHH38104.1};
OS Clostridium grantii DSM 8605.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1121316 {ECO:0000313|EMBL:SHH38104.1, ECO:0000313|Proteomes:UP000184447};
RN [1] {ECO:0000313|EMBL:SHH38104.1, ECO:0000313|Proteomes:UP000184447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8605 {ECO:0000313|EMBL:SHH38104.1,
RC ECO:0000313|Proteomes:UP000184447};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FQXM01000004; SHH38104.1; -; Genomic_DNA.
DR RefSeq; WP_073337275.1; NZ_FQXM01000004.1.
DR AlphaFoldDB; A0A1M5SHS8; -.
DR STRING; 1121316.SAMN02745207_00947; -.
DR OrthoDB; 9804124at2; -.
DR Proteomes; UP000184447; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR CDD; cd06576; PASTA_Pbp2x-like_1; 1.
DR CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR011927; SpoVD_pbp.
DR NCBIfam; TIGR02214; spoVD_pbp; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 2.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SMART; SM00740; PASTA; 2.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 2.
DR PROSITE; PS51178; PASTA; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000184447};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 594..660
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 664..723
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
SQ SEQUENCE 726 AA; 79924 MW; DB07B653C4E571CB CRC64;
MNKNQYSDKV IMKRRMLYTV SFLLLLFFGL FIRLGYIMLV KAKDYNPIAV QQWTEDVKID
AKRGQILDRN GNELAVSANV YRVDFDLNTL RKVQESKGLS NEDIAIKISN VIDIEKDKVL
GILEKTLPGG LPMKSATLIR RIEKTEADNI RALGINGIIV SPDTARYYPN DNFLAHVLGH
TNSDGEGLTG VELMYNSYLA GTPGILIAET DAKSQEIGNT ISEYIPPIAG KNLILTIDEM
IQHFAEKAAD QALIDNKAKA VTIIISNPNN GEILAMVNKP DYDPNNPWID GLSFEELQQS
WRNRAVSDTY EPGSIFKVVT ATAAMAEKVI DEDTYEIVCN GSTTIGKKII HCWKRTGHGT
QAFVDILRNS CNVGFMNLAE KLGAEALNKH IKLFGLGEKT GIDLPGEAKG IIKKTENITA
TDLATISFGQ TNTLTPIQYV QVINAIANGG KLITPHVMKE IQWTDENNEN QTIQYDNSNV
RQVEDPVVME RLRGYLEEVI TTGGGGKAYV EGYNIGGKTG TAQKVVDGKY AAQTYVASFG
GMAPILPGKT PDLTVFISID EPDPSNYYAG QIAAPVAKQI FVDVFNYLDM VNINSSKDEL
LSDVIVPEIR GSKKSEALSV LKESKLNYEI SGDGEYVTDT TPKPGYTTKE NSKIIVYTGS
NNPVTNDIIV PNFNGLTEEA AIEILNDLGL KYEFNGEGLI SHQSIEFKQK VSKNTLITFE
LEIIGD
//
