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Database: UniProt
Entry: A0A1M5SS59_9RHOB
LinkDB: A0A1M5SS59_9RHOB
Original site: A0A1M5SS59_9RHOB 
ID   A0A1M5SS59_9RHOB        Unreviewed;       489 AA.
AC   A0A1M5SS59;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   16-JAN-2019, entry version 13.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=SAMN04488044_2476 {ECO:0000313|EMBL:SHH41414.1};
OS   Cognatishimia maritima.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Cognatishimia.
OX   NCBI_TaxID=870908 {ECO:0000313|EMBL:SHH41414.1, ECO:0000313|Proteomes:UP000184211};
RN   [1] {ECO:0000313|EMBL:SHH41414.1, ECO:0000313|Proteomes:UP000184211}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 28223 {ECO:0000313|EMBL:SHH41414.1,
RC   ECO:0000313|Proteomes:UP000184211};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; FQWM01000005; SHH41414.1; -; Genomic_DNA.
DR   Proteomes; UP000184211; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000184211};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184211}.
FT   DOMAIN      181    311       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      397    466       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     189    196       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   489 AA;  55202 MW;  75DFEE0E232EFF9D CRC64;
     MPMRPWIWER QRRGIAPQGK AQKRGQMEQE QWGSLQQDLL NTVGQNNYKA WIEPLRLTEL
     ADGVATFSVP TNFIGNYVSQ NFGDLIIHQL TKAGEDVQRI HFRVGRAAAN QNGAASPSIA
     PASAPKAATS RSTPTRAAAL KDELPGAPLD TRFTFDSFVV GKPNELANAA ARRVAEGGPV
     SFNPLFLYGG VGLGKTHLMH AIAWELQTQR PDLNVLYLSA EQFMYRFVQA LRDRKMMDFK
     ELFRSVDVLM VDDVQFIAGK DSTQEEFFHT FNALVDQNKQ IIISADRAPG EIKDMEDRIR
     SRLQCGLVVD LHPTDYELRL GILQSKVDQY RGQYPDLQIA DGVLEFLAHR ISTNVRVLEG
     ALTRLFAFAS LVGREITMDL TQDCLSDVLR ASERKISVEE IQRRVAEHYN IRLSDMIGPK
     RVRTFARPRQ VAMFLCKQLT SRSLPEIGRR FGGRDHTTVM HGVRRIEELR SSDGQIAEDL
     ELLRRALEA
//
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