ID   A0A1M5TB03_9ACTN        Unreviewed;       679 AA.
AC   A0A1M5TB03;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=phospholipase C {ECO:0000256|ARBA:ARBA00012018};
DE            EC=3.1.4.3 {ECO:0000256|ARBA:ARBA00012018};
GN   ORFNames=SAMN05443575_3956 {ECO:0000313|EMBL:SHH47881.1};
OS   Jatrophihabitans endophyticus.
OC   Bacteria; Actinomycetota; Actinomycetes; Jatrophihabitantales;
OC   Jatrophihabitantaceae; Jatrophihabitans.
OX   NCBI_TaxID=1206085 {ECO:0000313|EMBL:SHH47881.1, ECO:0000313|Proteomes:UP000186132};
RN   [1] {ECO:0000313|EMBL:SHH47881.1, ECO:0000313|Proteomes:UP000186132}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45627 {ECO:0000313|EMBL:SHH47881.1,
RC   ECO:0000313|Proteomes:UP000186132};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-
CC         sn-glycerol + H(+) + phosphocholine; Xref=Rhea:RHEA:10604,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17815,
CC         ChEBI:CHEBI:57643, ChEBI:CHEBI:295975; EC=3.1.4.3;
CC         Evidence={ECO:0000256|ARBA:ARBA00023550};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:10605;
CC         Evidence={ECO:0000256|ARBA:ARBA00023550};
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC       {ECO:0000256|ARBA:ARBA00004191}.
CC   -!- SIMILARITY: Belongs to the bacterial phospholipase C family.
CC       {ECO:0000256|ARBA:ARBA00009717}.
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DR   EMBL; FQVU01000006; SHH47881.1; -; Genomic_DNA.
DR   RefSeq; WP_073392145.1; NZ_FQVU01000006.1.
DR   AlphaFoldDB; A0A1M5TB03; -.
DR   STRING; 1206085.SAMN05443575_3956; -.
DR   OrthoDB; 4181857at2; -.
DR   Proteomes; UP000186132; Unassembled WGS sequence.
DR   GO; GO:0034480; F:phosphatidylcholine phospholipase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:InterPro.
DR   CDD; cd16014; PLC; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 2.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR017767; Bact_PC-PLC.
DR   InterPro; IPR007312; Phosphoesterase.
DR   InterPro; IPR008475; PLipase_C_C.
DR   InterPro; IPR006311; TAT_signal.
DR   NCBIfam; TIGR03396; PC_PLC; 1.
DR   PANTHER; PTHR31956:SF8; ACID PHOSPHATASE PHOA (AFU_ORTHOLOGUE AFUA_1G03570); 1.
DR   PANTHER; PTHR31956; NON-SPECIFIC PHOSPHOLIPASE C4-RELATED; 1.
DR   Pfam; PF04185; Phosphoesterase; 1.
DR   Pfam; PF05506; PLipase_C_C; 2.
DR   PROSITE; PS51318; TAT; 1.
PE   3: Inferred from homology;
KW   Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186132};
KW   Secreted {ECO:0000256|ARBA:ARBA00022512};
KW   Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT   DOMAIN          499..580
FT                   /note="Bacterial phospholipase C C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05506"
FT   DOMAIN          595..663
FT                   /note="Bacterial phospholipase C C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05506"
FT   REGION          462..498
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   679 AA;  74676 MW;  2DB7CD693F30142D CRC64;
     MSELDRRRFL QLAGGGLAAS ALAQTFGESI ARAAAIPASR RHGSLRDVEH IVVLMQENRS
     FDHYLGTMRG VRGFGDPHPA VLPSGRSVWH QSDGTREVLP YRPDHDDLGM AFLEGTPHGW
     PDTHEAFHDG HYDRFVPAKT QTTMTHLRRG DMPFQFALGD AFTVCDGYHC STMTSTDPNR
     YYMWTGWVGN DGAGKGPVVT NAEAGYAWTT YPERLERAGV SWKIYQDVGT GLDAAGSWGW
     TDDAYIGNYG DNSLLYFDNY RNARPGDALY EKARRGTNAA AGDGYFDILR ADVAAGRLPQ
     ISWIAAPEAF CEHPNWPVNY GAWYVSQVLD ALTSDPDVWS KTVLLVTYDE NDGYFDHVVP
     PYPNTDQLAG ASTVPTVDEV YRGTEFAPAP YGLGQRVPMF VVSPWSTGGW VCSETFDHTS
     IIRLMEARFG VREPNITPWR RAVCGDLTSA FDFSRHRAAA PDLPSTAGYR PPDRARHDSF
     VPVPPEPGRL PSQEAGVRPS RPLGYRLDVS ATVRDDGLAL AMRNAGRLGV HLQARSQTGA
     APVSFTVGAK DSLTASLPVS GRYDIALHGP HGFFRRFAGD AADVDTEAWV TTHGDRIELV
     LVNRGRAAVT FRVADAYGRA RTVRVRGRDR VGVRVSTERQ HGWYDLTVTH PGTDGFRRAM
     AGRVETGRPS VSDPQLSGR
//