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Database: UniProt
Entry: A0A1M5TR12_9BURK
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Original site: A0A1M5TR12_9BURK 
ID   A0A1M5TR12_9BURK        Unreviewed;       349 AA.
AC   A0A1M5TR12;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   08-MAY-2019, entry version 7.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=SAMN05428948_4325 {ECO:0000313|EMBL:SHH53207.1};
OS   Massilia sp. CF038.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Oxalobacteraceae; Massilia.
OX   NCBI_TaxID=1881045 {ECO:0000313|EMBL:SHH53207.1, ECO:0000313|Proteomes:UP000184361};
RN   [1] {ECO:0000313|EMBL:SHH53207.1, ECO:0000313|Proteomes:UP000184361}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CF038 {ECO:0000313|EMBL:SHH53207.1,
RC   ECO:0000313|Proteomes:UP000184361};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; FQWU01000004; SHH53207.1; -; Genomic_DNA.
DR   RefSeq; WP_073222011.1; NZ_FQWU01000004.1.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000184361; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000184361};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184361};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       45    341       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   349 AA;  37507 MW;  52C32BCB8CEF72D0 CRC64;
     MKRDLLAGFE EPRSIAMPSP AELRAMLPLP ATASLAVAAG RRAIRDILER RDQRLLVVVG
     PCSIHDPVAA LDYAERLAGL AREVADSMLV VMRVYFEKPR TSTGWKGLIN DPHLDDSFRV
     AEGMHMARRL LLEVSALGLP AAVEALDPVS PHYLNDLIGW AAIGARTTES QTHREMASGL
     PVPVGFKNGT DGSVDTAINA IRAAGRSHAY LGIDAQGRAA VVHTDGNPHA HLVLRGGSSG
     PNYDAASVAR AERAMREADM RPTILVDCAH GNSSKDHRRQ SLVLEDVIAQ KLNGNDSIVG
     VMIESFIEAG NQPMAASRSQ LRYGCSVTDP CVDWPTTQAM LRLAHGALQ
//
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