ID A0A1M5U2V2_9ACTN Unreviewed; 349 AA.
AC A0A1M5U2V2;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Cation diffusion facilitator family transporter {ECO:0000313|EMBL:SHH57357.1};
GN ORFNames=SAMN05444521_0978 {ECO:0000313|EMBL:SHH57357.1};
OS Streptomyces sp. 3214.6.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1882757 {ECO:0000313|EMBL:SHH57357.1, ECO:0000313|Proteomes:UP000190947};
RN [1] {ECO:0000313|Proteomes:UP000190947}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3124.6 {ECO:0000313|Proteomes:UP000190947};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; LT670819; SHH57357.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M5U2V2; -.
DR STRING; 1882757.SAMN05444521_0978; -.
DR Proteomes; UP000190947; Chromosome i.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006829; P:zinc ion transport; IEA:InterPro.
DR Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR InterPro; IPR002524; Cation_efflux.
DR InterPro; IPR027469; Cation_efflux_TMD_sf.
DR InterPro; IPR040177; SLC30A9.
DR NCBIfam; TIGR01297; CDF; 1.
DR PANTHER; PTHR13414; HUEL-CATION TRANSPORTER; 1.
DR PANTHER; PTHR13414:SF9; ZINC TRANSPORTER 9; 1.
DR Pfam; PF01545; Cation_efflux; 1.
DR SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000190947};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 42..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 349 AA; 36564 MW; FA2743385020C748 CRC64;
MSTADRTSEH TTGHTSEHTT GPSSQHTSDR TTGRAADRRT RLTVLLALAA NLVIAVAKAV
GGVIAGSPAL LSEAAHSVAD SLNEVFLLAA LRRSRRPADE RHPFGYGKER FFWSLLAAVG
IFVMGGCFSV FQGVEALRTG ADETFSGYVV GLIVLGVAFL AEGVSLLRAL HQVHRQGGGL
AGLRDPALRT VVAEDGTAVL GVTLAAIGMV LHMVTGQVVW EAGASVAIGV LLVYVAYGLG
RAARDQLIGE AADPETGARI RALLDAQPEI DSVEALFTMK TGLDSTLVAA RVDLMPGLDS
ERVEEVAVRI KRSIARTTPE AAPIFLDVTD RPAREGRESP AATGERGGA
//
