ID A0A1M5UR58_9ACTN Unreviewed; 676 AA.
AC A0A1M5UR58;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:SHH65193.1};
GN ORFNames=SAMN05443575_4277 {ECO:0000313|EMBL:SHH65193.1};
OS Jatrophihabitans endophyticus.
OC Bacteria; Actinomycetota; Actinomycetes; Jatrophihabitantales;
OC Jatrophihabitantaceae; Jatrophihabitans.
OX NCBI_TaxID=1206085 {ECO:0000313|EMBL:SHH65193.1, ECO:0000313|Proteomes:UP000186132};
RN [1] {ECO:0000313|EMBL:SHH65193.1, ECO:0000313|Proteomes:UP000186132}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45627 {ECO:0000313|EMBL:SHH65193.1,
RC ECO:0000313|Proteomes:UP000186132};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; FQVU01000009; SHH65193.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M5UR58; -.
DR STRING; 1206085.SAMN05443575_4277; -.
DR Proteomes; UP000186132; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000186132}.
FT DOMAIN 41..218
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 266..647
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 676 AA; 72032 MW; 2D279CF2DA0003CB CRC64;
MIALVASMML TLFARLYYVQ LLDPDKPQQS AHLTHDAKIV IPAPRGLIVD ANGTPLVANT
SVQQVTVTRD VLQRRADKGR AVLARLASLL DTSAALLAKQ ITPCSPKVPA PCSTGKPFAP
VTVSQRAPQR VVLAISEHRE DYPGVAVQTV SVPSYPNASL AAHLLGYTSQ ITAADKSRNS
ALDDVDTIGV SGLEEQYDAA LRGIDGEQVV RLSPQGLAVG TGATTRAQQG DTLVTSIDGR
LQALAEKSLA QQIKDSRKAG KAAPSGAVVI MDPQTGRIVA SASYPTYDPT VFVGGVSNRE
YAKLTSTAAN TPLLNRAIAG QYAPGSTFKL ITSSSLVEHG QINLTDRYGC PGSLTIDGRV
KTNFESESLG PIDLRDALGY SCDTFFYRPT AGEYYADQKR VAKDEKPREW LQAMARAYGV
GTSPGVDLPA GEQSSGGYAD RESRLARWKA NRATYCANGR RGYPEVKDAK QRAYLTLLAK
ENCTDGWRYR AGDNADMSIG QGETTMSPLQ LAAAYSALVN GGRLFEPTLG KAVVDGHGKV
VKSIDAKVRR TVPVSQQTLD YIARSLNFGR GYAVSGAFAY LKSGYKGRIG GKTGTAEVEG
KQDTSWLASW GPTYSKGGHV RARFVMVGMV EQAGTGATAA GPMLKRIWDG IFGVGSTPVV
AHERPRTTLP KVEAGR
//
