ID A0A1M5UT78_9FIRM Unreviewed; 689 AA.
AC A0A1M5UT78;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN ORFNames=SAMN02746098_01067 {ECO:0000313|EMBL:SHH66144.1};
OS Desulfosporosinus lacus DSM 15449.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfosporosinus.
OX NCBI_TaxID=1121420 {ECO:0000313|EMBL:SHH66144.1, ECO:0000313|Proteomes:UP000183954};
RN [1] {ECO:0000313|EMBL:SHH66144.1, ECO:0000313|Proteomes:UP000183954}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15449 {ECO:0000313|EMBL:SHH66144.1,
RC ECO:0000313|Proteomes:UP000183954};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364093}.
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DR EMBL; FQXJ01000004; SHH66144.1; -; Genomic_DNA.
DR RefSeq; WP_073028390.1; NZ_FQXJ01000004.1.
DR AlphaFoldDB; A0A1M5UT78; -.
DR STRING; 1121420.SAMN02746098_01067; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000183954; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:SHH66144.1};
KW Cilium {ECO:0000313|EMBL:SHH66144.1};
KW Flagellum {ECO:0000313|EMBL:SHH66144.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 39..58
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 111..129
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 197..219
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 239..260
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 281..314
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 689 AA; 75363 MW; 0C5A1072055A1FF5 CRC64;
MSTSVKSRIL NNTDIIAALG LVSIVVMMVV PLPAGLLDIL ITLNITASVL TLMLAVFAQD
PLEFSALPSL LLTLTLFRLS LNISATRLIL LDGHAGEIIQ QFGEFVIRGD AVVGFIIFII
LVLVQFIVIT KGAERVSEVA ARFTLDAMPG KQMSIDADLN AGMINEQQAR DRRKAIQQEA
DFYGAMDGST KFVKGDAIAA IIILFINIIG GFITGVVMQD MPLLEALHKY TLLTIGDGLV
SQIPALLIST ATGLVVTRAA SDSNLGEDLV KQLFKKPKAL FITAGVLSML AFLGLPKFPL
FLVSAALIGM GVMLQRNSKV SVVKESAVAR ETEIEESKKP ENVLNLLHVD HMELELGYAL
IALVDVQQGG DLLDRIVLIR RQIASELGFI VPVIRVRDNM NLQPNQYVIK IRGSEIATSE
ILADHYMAMS GGADDSEIPG TPTKEPSFGL DAKWINAMYR EQAELSGWMV VDAPTVLATH
ITEVIKTQAW EILNRQDVKA LIDHAKELAP AVVDELIPDM LSLGQVQKVL ANLLRERVSI
KDMVSILENL ADYASVTKDL DRLTEHVRQA LARQILQPLL GKDKNLPVIT LDPQIEQQIL
DSIQPSEYGT YLALDPKVLH VLMQNLTREV EKVVLKGLTP VIVCAPLVRI NLKRVTERQL
PQLMVLSYNE LVQGVQVQAV GMVGMDLAS
//
