ID   A0A1M5UZL7_9CLOT        Unreviewed;       639 AA.
AC   A0A1M5UZL7;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC {ECO:0000313|EMBL:SHH68133.1};
GN   ORFNames=SAMN02745207_02002 {ECO:0000313|EMBL:SHH68133.1};
OS   Clostridium grantii DSM 8605.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1121316 {ECO:0000313|EMBL:SHH68133.1, ECO:0000313|Proteomes:UP000184447};
RN   [1] {ECO:0000313|EMBL:SHH68133.1, ECO:0000313|Proteomes:UP000184447}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 8605 {ECO:0000313|EMBL:SHH68133.1,
RC   ECO:0000313|Proteomes:UP000184447};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
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DR   EMBL; FQXM01000009; SHH68133.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1M5UZL7; -.
DR   STRING; 1121316.SAMN02745207_02002; -.
DR   OrthoDB; 9803111at2; -.
DR   Proteomes; UP000184447; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF13727; CoA_binding_3; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184447};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        15..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        42..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        76..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        104..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          289..571
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   639 AA;  72696 MW;  13FD44A97ADF3D0A CRC64;
     MKKLFNKIKI RQKKIILLIS DIIFVNVGYL FVLFLFNERY KGIFITAFLV TSIYISIFTL
     FRLYDSLWKV AGSYEFFNVI KANLLSWGIF YGVNFYMMNS KFDFVIYFIF FIFTLSLTFS
     FRICYRFLRR YMIFSYGNSS NCCKVEKRVM IIGAGYTGSL IIKEMLSNKQ DGYNPVVIID
     DDKSKWGNYI NKVKIVGGRN KIIPTAISEN IDVIVIAIAK IQQTNKKSII NICKNTGCKL
     KIIPSYNEIL NEKVFLSKIR DVNVEDLLGR DPVQLDMENI SDYIKDKTVL VTGGGGSIGS
     EICRQVSKFK PKKLLVLDIY ENNAYDLQNE LKTTYSELDM QVIIASVRDK NRLENIFAKY
     RPEVVFHAAA HKHVPLMEEN PGEAIKNNIF GTLNTAECAD KFGVKKFVLI STDKAVNPTN
     IMGATKRVCE MIVQSMNNIS ETSFVAVRFG NVLGSNGSVI PLFKNQIRSG GPVTLTHKDI
     IRFFMTIPEA AQLVLQAGAY ANGGEIFVLD MGPAVKIYDL ACDLIKLSGL EPNKDIKIEI
     TGLRPGEKLY EELLMDGELN GQTKHNKIYI GKVSNTDFYR LRNKLNRIRL IISNEDDELI
     YAIMKDLVPT FNPKCMQINS NNEEFDFDLE EGNVAVTLE
//