ID A0A1M5VAU7_9FIRM Unreviewed; 757 AA.
AC A0A1M5VAU7;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=HD/PDEase domain-containing protein {ECO:0000259|SMART:SM00471};
GN ORFNames=SAMN02746098_01277 {ECO:0000313|EMBL:SHH72331.1};
OS Desulfosporosinus lacus DSM 15449.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfosporosinus.
OX NCBI_TaxID=1121420 {ECO:0000313|EMBL:SHH72331.1, ECO:0000313|Proteomes:UP000183954};
RN [1] {ECO:0000313|EMBL:SHH72331.1, ECO:0000313|Proteomes:UP000183954}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15449 {ECO:0000313|EMBL:SHH72331.1,
RC ECO:0000313|Proteomes:UP000183954};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FQXJ01000004; SHH72331.1; -; Genomic_DNA.
DR RefSeq; WP_073028644.1; NZ_FQXJ01000004.1.
DR AlphaFoldDB; A0A1M5VAU7; -.
DR STRING; 1121420.SAMN02746098_01277; -.
DR OrthoDB; 9806952at2; -.
DR Proteomes; UP000183954; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 420..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 500..655
FT /note="HD/PDEase"
FT /evidence="ECO:0000259|SMART:SM00471"
FT REGION 710..757
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 715..745
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 757 AA; 83624 MW; 0CA4AD83E0929E8C CRC64;
MMVLKIKMFK TIWDELSSRF DWLKHHTTWF RAIVGVMYFL LLTVLLSSNI FVSTLHLEVG
EPSPQLITAP WTRVIVDQAK YTRDKEAAAK AVPPVYKPDE EYLTLLTKEV GSAFISLREA
SDDNDISISE LKKLEPFASL PESLLTSLIE TVPDELDKAE KAGRDIILNK ARSLETGART
SEDMPAFRDR TKADLDQSEL NEDFKVFFKA FVDREVTQPT LIVDEATMDV LRAAARTAIK
QEELHYKANQ KIVGVGDIVD ETIYEVLVAY GLINNQNTGK SVAGIAMIVL IGMGSILLYL
FQYKRDIFRM TNRLVLIGLT ISLVLAIGRA VIALNLGTDF NSLSGMLIPI AWATMTVAIL
VGVDIAIMVS LVLAVFVSVL VDPALSTSFG LHSGVVALFG GIVGVYSVSR LSQRSDLARA
GIFVSAVNVL VISGIALTSD MRLAVWVVGV ILGIVNGLAS SFLTVGALHW FESGFHITSS
VRLLELSDPN RPLLKRLLLE APGTYHHSIL VGNLAEAAAE AVQADATLVR VASMYHDIGK
LKRPYFFIEN QFTQDNPHDK IAPTLSSLII TSHVKDGLEL AKDNKLPVQI QDIIAQHHGD
SLVSFFYHKA LEEYENVPEE TFHYEGPKPQ TKEAALVALA DNVEAAVRSM KQPTPGRVEG
FVRKIIKDKL NDGQLDQCDL TFQDLDRIAM AFVRVLSGIF HSRVEYPEMP GIRESNNHSM
HKKLVDEVGQ EDDASSQKEK QPESPEGTVE SIVSREG
//
