ID A0A1M5WU12_9CLOT Unreviewed; 819 AA.
AC A0A1M5WU12;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:SHH91079.1};
GN ORFNames=SAMN02745207_03134 {ECO:0000313|EMBL:SHH91079.1};
OS Clostridium grantii DSM 8605.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1121316 {ECO:0000313|EMBL:SHH91079.1, ECO:0000313|Proteomes:UP000184447};
RN [1] {ECO:0000313|EMBL:SHH91079.1, ECO:0000313|Proteomes:UP000184447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8605 {ECO:0000313|EMBL:SHH91079.1,
RC ECO:0000313|Proteomes:UP000184447};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FQXM01000020; SHH91079.1; -; Genomic_DNA.
DR RefSeq; WP_073339449.1; NZ_FQXM01000020.1.
DR AlphaFoldDB; A0A1M5WU12; -.
DR STRING; 1121316.SAMN02745207_03134; -.
DR OrthoDB; 9762141at2; -.
DR Proteomes; UP000184447; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000184447};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 235..285
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 422..555
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 564..818
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT COILED 353..387
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 819 AA; 94529 MW; A706E6B1C05D94E3 CRC64;
MTILIIIYLT CSSICLFIGF SILLNNSRQK FNRWFFIVCM NLSFWALMLS FMTAAKDAET
VALYRRLTTF SWSTVFSGIL YVTIFLVKKE NFFKKIWSYI LVFSPAVLST YLYYSQPLKP
ENFVKTGFGW IIEYPETRGI LRDYFFNFYY VIFTAIIILL FINWGKNTEF EREKKQSKII
VYSIIVAFIL GTITDVILPN LGFVNIPELS IITNLIVVLS IWYAVIKYSF MSLNIENIVV
DVFKIMNEGL IILDSKKIIV DINQGALELL GYEENEIKGK NIEIIFSNKQ ETDKIETLNS
YEIDLLSKNY TNIPVLLSSS ILDDGWGGDM GRLIIFQNHC EIRKMQNKLK EAYNGLEKRV
NQRTIELKEV NAQLENEIQG RIQKEEEIKK LAFNDQLTGL ANRKCFADQV NERIFESSKH
KKTFSILLID LDSFKMINDT IGYEQGEKLL IKVSERLKGI LRSNDIIARA TGDQFLILIE
DYNCNEDIEK KCEYIINKIK EPYQFNNSEI YITASIGASI YPHHGIEAEK LLNNADIAMY
KAKEKGKGRF VFFDSLMKKN LDEVMNLTND LYRALEFNEL EVYYQPQINI KSSKIVGLEA
LLRWNHPKLG IVSPNIFIPI AEKTGLIVSI GEWVLNTACR QVKQWQEAGV CNLSIAVNLS
VNQIQSNKIV EQVSKILAET ELNPEDLELE ITENVLMKDT NFVVDTLKEL KQLDIRIAID
DFGTEYSSLN YLKQLPLDRI KIAKCFVDGI DKNINDEAII SAIILLGKKL KLNVIAEGIE
EERQQIFLKA QMCDEIQGFY YYKPMPAMEI EKILKKSNN
//
