ID A0A1M5XUG6_9BURK Unreviewed; 319 AA.
AC A0A1M5XUG6;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Lactate dehydrogenase {ECO:0000313|EMBL:SHI03396.1};
GN ORFNames=SAMN04488135_107147 {ECO:0000313|EMBL:SHI03396.1};
OS Pollutimonas bauzanensis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Pollutimonas.
OX NCBI_TaxID=658167 {ECO:0000313|EMBL:SHI03396.1, ECO:0000313|Proteomes:UP000184226};
RN [1] {ECO:0000313|EMBL:SHI03396.1, ECO:0000313|Proteomes:UP000184226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.10190 {ECO:0000313|EMBL:SHI03396.1,
RC ECO:0000313|Proteomes:UP000184226};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00005854,
CC ECO:0000256|RuleBase:RU003719}.
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DR EMBL; FQXE01000007; SHI03396.1; -; Genomic_DNA.
DR RefSeq; WP_073104051.1; NZ_FQXE01000007.1.
DR AlphaFoldDB; A0A1M5XUG6; -.
DR STRING; 658167.SAMN04488135_107147; -.
DR OrthoDB; 9805416at2; -.
DR Proteomes; UP000184226; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd12156; HPPR; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029752; D-isomer_DH_CS1.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000184226}.
FT DOMAIN 24..315
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 112..285
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 319 AA; 33982 MW; BCA72360B7E9205A CRC64;
MSTAKPALLQ LLPLPFSDAH PPLATHFDVI ELWKESEPDA VIAARSNDIT VLVTNAMTPT
RAELIDRLPN LRAICSNGVG YDAIDVKHAQ QKGIQVSNTP DVLNDCVADL ALGLLLATAR
RLGQADRYVR ANQWGGDAKF PLGVKVSHKK LGIVGLGRIG MAIAQRAAGF NMEIRYHNRR
QRSDVDLPYE ASLAGLAAWA DFLVIATVGG ASTHHLVDRQ VLQALGPEGI LVNISRGSVV
DEKALVDALA GGELGGAGLD VYESEPHVPD ALKTLDNVVI APHIASATTE TRRAMADLVV
DNVEAYMATG KVLTPIPPL
//
