ID A0A1M5Y821_9FIRM Unreviewed; 646 AA.
AC A0A1M5Y821;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:SHI07958.1};
GN ORFNames=SAMN02746098_02325 {ECO:0000313|EMBL:SHI07958.1};
OS Desulfosporosinus lacus DSM 15449.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfosporosinus.
OX NCBI_TaxID=1121420 {ECO:0000313|EMBL:SHI07958.1, ECO:0000313|Proteomes:UP000183954};
RN [1] {ECO:0000313|EMBL:SHI07958.1, ECO:0000313|Proteomes:UP000183954}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15449 {ECO:0000313|EMBL:SHI07958.1,
RC ECO:0000313|Proteomes:UP000183954};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FQXJ01000007; SHI07958.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M5Y821; -.
DR STRING; 1121420.SAMN02746098_02325; -.
DR Proteomes; UP000183954; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00077; HDc; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13487; HD_5; 1.
DR Pfam; PF13426; PAS_9; 2.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS51832; HD_GYP; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 65..121
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 140..192
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 350..485
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 471..646
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
FT DOMAIN 493..615
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
SQ SEQUENCE 646 AA; 74252 MW; 36AB68D2891CDF47 CRC64;
MDNNSLFTVI SLLALLFYIL VRLISNFRHK NEELQAYIQQ VTATQEELRL QYNQNVENEK
KLIISEEKFR TMFEQAPLGI ALSDTLTGKL YQINPKFAEI VGREIEETVG IDWMSITHPD
DVQGNLKNSV LVNDKKIKGF NMSKRYIKPD GSVVWAKITV ATLNLEYEGS ISEICMVEDI
TEQKLNEDAL KSSEYTFRRL FEGSSDAILL LENYKVIDCN PAAIEFLGYD SKGKIVGKTT
WELSPERQPD GISSMEKAMD INKYAQNNGK YKFEWWLRKE NGIEFPVEIM LTPILLNGKQ
VSHAIWRDVS ERKLLEQKLE YLSYKDVLTG LYNRRFFEEE LKRLNVQRNL PLTIVMADVN
GLKLINDSFG HAMGDELLKK VGQVIVRGCR GDDIIARLGG DEFVILLPKT DTNETEQIVK
RIKENALKET IGSIEISISF GWETKIDREE DIREILKKAE DYMYKRKLYE SPSMRGKTIN
AIIRTLHEKN KREEQHSHRV SALCECMGKA LGLPEGEVEE LKTVGLLHDI GKVAIEETTL
NKTGALTEDE WQDIKRHPEI GYRILSTVND MAEIAEYILY HHERWNGHGY PRGLKGEEIP
FQSRIIAIVD AFDAMTSERS YRSALPEEVA IEELLKNSGI QLILKW
//
