ID A0A1M5YTK8_BUTFI Unreviewed; 458 AA.
AC A0A1M5YTK8;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Flagellar biosynthesis protein FlhF {ECO:0000256|ARBA:ARBA00014919};
DE AltName: Full=Flagella-associated GTP-binding protein {ECO:0000256|ARBA:ARBA00030866};
GN ORFNames=SAMN02745229_01700 {ECO:0000313|EMBL:SHI15396.1};
OS Butyrivibrio fibrisolvens DSM 3071.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Butyrivibrio.
OX NCBI_TaxID=1121131 {ECO:0000313|EMBL:SHI15396.1, ECO:0000313|Proteomes:UP000184278};
RN [1] {ECO:0000313|EMBL:SHI15396.1, ECO:0000313|Proteomes:UP000184278}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3071 {ECO:0000313|EMBL:SHI15396.1,
RC ECO:0000313|Proteomes:UP000184278};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Necessary for flagellar biosynthesis. May be involved in
CC translocation of the flagellum. {ECO:0000256|ARBA:ARBA00025337}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the GTP-binding SRP family.
CC {ECO:0000256|ARBA:ARBA00008531}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FQXK01000013; SHI15396.1; -; Genomic_DNA.
DR RefSeq; WP_073387006.1; NZ_FQXK01000013.1.
DR AlphaFoldDB; A0A1M5YTK8; -.
DR STRING; 1121131.SAMN02745229_01700; -.
DR GeneID; 40457291; -.
DR OrthoDB; 9778554at2; -.
DR Proteomes; UP000184278; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR CDD; cd17873; FlhF; 1.
DR Gene3D; 1.20.120.1380; Flagellar FlhF biosynthesis protein, N domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR020006; FlhF.
DR InterPro; IPR047040; FlhF__GTPase_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000897; SRP54_GTPase_dom.
DR NCBIfam; TIGR03499; FlhF; 1.
DR PANTHER; PTHR43134:SF3; FLAGELLAR BIOSYNTHESIS PROTEIN FLHF; 1.
DR PANTHER; PTHR43134; SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA; 1.
DR Pfam; PF00448; SRP54; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00962; SRP54; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|ARBA:ARBA00022795};
KW Bacterial flagellum protein export {ECO:0000256|ARBA:ARBA00023225};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000313|EMBL:SHI15396.1};
KW Cilium {ECO:0000313|EMBL:SHI15396.1};
KW Flagellum {ECO:0000313|EMBL:SHI15396.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 259..408
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 260..454
FT /note="SRP54-type proteins GTP-binding"
FT /evidence="ECO:0000259|SMART:SM00962"
FT REGION 65..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 458 AA; 50788 MW; 5E57AA5CDD307C4F CRC64;
MIIKKFVGKT EEDATEQARE ELGAGIVVMN VRPVRKVGFW SFFQKPKTEV TVALEEEPDL
ADKIVRPKKS TITPEQSDSK PSETVDPSKK LIKASQSGVL PPLKVGGSST SSKIADINAV
VAENATASSV VLERPGVTVT PSSSVIEEKL DSLHSLLEKN IVRPQKENEA SNASDDKGDN
VVVHAKDDTI PEETLSFIKL LYNTMIENEV DEHYVNDLTD EVERFAKPGV PLEYFLSNVY
QKMILKFGNP EEIKPSENGV KAEIFIGPTG VGKTTTIAKL ASKLTVVEHK KVALITVDTY
RIAAAEQLRT YASILEIPFR VIYSVDDIKK AADDFSDMDY IMVDTAGHSI HNEEQRSEVG
SYVKALKEKM DTDTFLVMSA STKYRDLLEI VDNYKEDFDY KLIFTKMDET NAVGNLYNLR
LHTGAPMSYI TNGQNVPDDI AVFDAQRVVK NLLGGKKK
//
