ID   A0A1M5Z6I3_9FIRM        Unreviewed;       277 AA.
AC   A0A1M5Z6I3;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=5-methyltetrahydrofolate--homocysteine methyltransferase {ECO:0000313|EMBL:SHI19866.1};
GN   ORFNames=SAMN02746098_03012 {ECO:0000313|EMBL:SHI19866.1};
OS   Desulfosporosinus lacus DSM 15449.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC   Desulfosporosinus.
OX   NCBI_TaxID=1121420 {ECO:0000313|EMBL:SHI19866.1, ECO:0000313|Proteomes:UP000183954};
RN   [1] {ECO:0000313|EMBL:SHI19866.1, ECO:0000313|Proteomes:UP000183954}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15449 {ECO:0000313|EMBL:SHI19866.1,
RC   ECO:0000313|Proteomes:UP000183954};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the vitamin-B12 dependent methionine synthase
CC       family. {ECO:0000256|ARBA:ARBA00010398}.
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DR   EMBL; FQXJ01000010; SHI19866.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1M5Z6I3; -.
DR   STRING; 1121420.SAMN02746098_03012; -.
DR   Proteomes; UP000183954; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0042558; P:pteridine-containing compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.20; Dihydropteroate synthase-like; 1.
DR   InterPro; IPR011005; Dihydropteroate_synth-like_sf.
DR   InterPro; IPR000489; Pterin-binding_dom.
DR   PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR   Pfam; PF00809; Pterin_bind; 1.
DR   SUPFAM; SSF51717; Dihydropteroate synthetase-like; 1.
DR   PROSITE; PS50972; PTERIN_BINDING; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:SHI19866.1};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SHI19866.1}.
FT   DOMAIN          8..253
FT                   /note="Pterin-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50972"
SQ   SEQUENCE   277 AA;  30753 MW;  BB6D699E839CF3CB CRC64;
     MKRGGPQMII IGEKINGTIP SVKKAIEQKD EEFIRSLAIR QTEAGADYLD VCASTSPDVE
     VDTLLWMMDI IQNAVDTPLC IDSPNPNVIE KVFPYAKRPG LINSVSEEGG KCEIIYPIIK
     GTKWEVIALT CDNRGIPKDI QTRVEITKVL VEKALTYDIS PDRIHIDPLV MALSADNQSL
     LNFVETLKEV KTLYPAIKVT SGLSNISFGM PLRKVVNQHF LTLAIDAGMD SAILDPCNRD
     LVTTLYITDA LLGKDRFCRN YLNAYRKNKI GPLKTDA
//