ID A0A1M6A190_9BACT Unreviewed; 397 AA.
AC A0A1M6A190;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=SAM-dependent methyltransferase /23S rRNA m(5)C-1962 methyltransferase {ECO:0000313|EMBL:SHI30267.1};
GN ORFNames=SAMN05720471_10185 {ECO:0000313|EMBL:SHI30267.1};
OS Fibrobacter sp. UWP2.
OC Bacteria; Fibrobacterota; Fibrobacteria; Fibrobacterales; Fibrobacteraceae;
OC Fibrobacter.
OX NCBI_TaxID=1896216 {ECO:0000313|EMBL:SHI30267.1, ECO:0000313|Proteomes:UP000184414};
RN [1] {ECO:0000313|EMBL:SHI30267.1, ECO:0000313|Proteomes:UP000184414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UWP2 {ECO:0000313|EMBL:SHI30267.1,
RC ECO:0000313|Proteomes:UP000184414};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RlmI family.
CC {ECO:0000256|ARBA:ARBA00038091}.
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DR EMBL; FQYM01000001; SHI30267.1; -; Genomic_DNA.
DR RefSeq; WP_073187218.1; NZ_FQYM01000001.1.
DR AlphaFoldDB; A0A1M6A190; -.
DR STRING; 1896216.SAMN05720471_10185; -.
DR OrthoDB; 9805492at2; -.
DR Proteomes; UP000184414; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd21153; PUA_RlmI; 1.
DR CDD; cd11572; RlmI_M_like; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR Gene3D; 3.30.750.80; RNA methyltransferase domain (HRMD) like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR041532; RlmI-like_PUA.
DR InterPro; IPR019614; SAM-dep_methyl-trfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR42873:SF1; METHYLTRANS_SAM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42873; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE; 1.
DR Pfam; PF10672; Methyltrans_SAM; 1.
DR Pfam; PF17785; PUA_3; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:SHI30267.1}; RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SHI30267.1}.
FT DOMAIN 2..87
FT /note="PUA"
FT /evidence="ECO:0000259|SMART:SM00359"
SQ SEQUENCE 397 AA; 44334 MW; FDA917B428CC17E3 CRC64;
MKAITLKAGR EKSALRYHPW IFSGAVDEVV GDPELGDTVE VYSYHSDFLG LAAYSPKSQI
RGRFWTFGEK ANIDREFFSN ILDRAIAARK SRGFDIADKE SAFRLINAEN DGIPGCIIDK
YGEIYSVEIL AAGAELHRKD IYELLAEKTG CRGIYERCDS DVRKKEGLPL RTGTVFGEVS
DEPVIINENG ILFPIDVKNG HKTGYYLDQR DARRRVGELA KGKKVLNCFC YTGGFGLYAL
RGGCDHVYQV DVSKDALKLA KDGIMRNKLA TAKATHVEAD VFQYLRKCRD KAETFDFIVL
DPPKFVESKD NLQKGARGYK DINLLAMKLL AEGGMLATFS CSGLMEMDLF QKIIADAAAD
AHRHMQIIER FGQPADHPVN TAFPEGQYLK GLLVQVF
//
