ID A0A1M6A303_9FLAO Unreviewed; 768 AA.
AC A0A1M6A303;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=galactosylceramidase {ECO:0000256|ARBA:ARBA00012657};
DE EC=3.2.1.46 {ECO:0000256|ARBA:ARBA00012657};
DE AltName: Full=Galactosylceramidase {ECO:0000256|ARBA:ARBA00033098};
GN ORFNames=SAMN05216261_0184 {ECO:0000313|EMBL:SHI30891.1};
OS Algibacter luteus.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Algibacter.
OX NCBI_TaxID=1178825 {ECO:0000313|EMBL:SHI30891.1, ECO:0000313|Proteomes:UP000184396};
RN [1] {ECO:0000313|EMBL:SHI30891.1, ECO:0000313|Proteomes:UP000184396}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.12213 {ECO:0000313|EMBL:SHI30891.1,
RC ECO:0000313|Proteomes:UP000184396};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 59 family.
CC {ECO:0000256|ARBA:ARBA00005637}.
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DR EMBL; FQYK01000001; SHI30891.1; -; Genomic_DNA.
DR RefSeq; WP_019386982.1; NZ_FQYK01000001.1.
DR AlphaFoldDB; A0A1M6A303; -.
DR STRING; 1178825.SAMN05216261_0184; -.
DR eggNOG; COG3408; Bacteria.
DR eggNOG; COG5520; Bacteria.
DR OrthoDB; 9806701at2; -.
DR Proteomes; UP000184396; Unassembled WGS sequence.
DR GO; GO:0004336; F:galactosylceramidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006683; P:galactosylceramide catabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR049162; GH59_C.
DR InterPro; IPR049161; GH59_cat.
DR InterPro; IPR001286; Glyco_hydro_59.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR15172; GALACTOCEREBROSIDASE; 1.
DR PANTHER; PTHR15172:SF1; GALACTOCEREBROSIDASE; 1.
DR Pfam; PF02057; Glyco_hydro_59; 1.
DR Pfam; PF21708; Glyco_hydro_59_C; 1.
DR PRINTS; PR00850; GLHYDRLASE59.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW Reference proteome {ECO:0000313|Proteomes:UP000184396};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Sphingolipid metabolism {ECO:0000256|ARBA:ARBA00022919}.
FT DOMAIN 158..468
FT /note="Glycosyl hydrolase family 59 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02057"
FT DOMAIN 607..766
FT /note="Glycosyl hydrolase family 59 C-terminal lectin"
FT /evidence="ECO:0000259|Pfam:PF21708"
SQ SEQUENCE 768 AA; 87342 MW; A290B2B375783036 CRC64;
MKQIVIYLWC LCSAAQAIQV KDLKCESQSN PTGITLARPS FSWTFIGNDI SQEQGGFRVM
MATSIEKLKY PDLWDTGPTS KSETGPYQYL GEPLKSGQKV YWRVTVWGNN RGVRHSEPAW
FEMGDIVNPE KAFEPPVFEQ KDGVVKINLN PKDEGRTFEG IGGVSAGAST DLLYDYKDPY
RDHILDILFK PKFGAGFQHL KVEMGGGENS TCGSEPSHAI TREELKNPVS RGYEFWFMRA
AKDRNPNMIL EYLPWSFPGY LKPNIYSKES AEYFVTFLDV AKRDWGLDID WVAAAENENY
TDRDWLVNEV RPMLDARGYK NVKIQGPDDN SGDWQIFEEL EKDPEFDKVI EAVGYHYVTG
REFTEDMVDG RGRPTTAKAK ASGRPLWASE DWSWTGKDWG GAGALNLARI YNKFYIRDKI
TKTLIWAPIG SIYKSVTWDK AGAMKANSPW SGYYEVWPTI WATAHTTQFA EANDWQYLDN
ACGLFDASTY KGSCVTMKNK NSSDWSMIIC TEEHETIEVA IEKGLSNTLV NVWKSSEKEQ
FVQLESIEPK NGSFTIKLDP KCIYSLTTTT GQQKGQYSIP EETPFPFPYK EDYEDRKVGD
LPKYHSDQTG SFEIVRKVDG TNCLKQINPE QGYDWMRVYR RSNIKPNTLV GDVTWTNFTC
SVDVFIEGGN VELGGRVQGS YLKGYRLMLE KNGNWTLVFD KQTLAQGSVE NFDANIWHKL
ELTFMDKEIE AFVDGHSITK VSHDKKSGYV MLGSSYDGNL FDNLEVMP
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