ID A0A1M6AC78_9VIBR Unreviewed; 268 AA.
AC A0A1M6AC78;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Precorrin-4 C(11)-methyltransferase {ECO:0000313|EMBL:SHI33988.1};
DE EC=2.1.1.133 {ECO:0000313|EMBL:SHI33988.1};
GN Name=cobM {ECO:0000313|EMBL:SHI33988.1};
GN ORFNames=VA7868_03537 {ECO:0000313|EMBL:SHI33988.1};
OS Vibrio aerogenes CECT 7868.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=1216006 {ECO:0000313|EMBL:SHI33988.1, ECO:0000313|Proteomes:UP000184608};
RN [1] {ECO:0000313|EMBL:SHI33988.1, ECO:0000313|Proteomes:UP000184608}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7868 {ECO:0000313|EMBL:SHI33988.1,
RC ECO:0000313|Proteomes:UP000184608};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005879}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FQXZ01000039; SHI33988.1; -; Genomic_DNA.
DR RefSeq; WP_073605138.1; NZ_FQXZ01000039.1.
DR AlphaFoldDB; A0A1M6AC78; -.
DR STRING; 1216006.VA7868_03537; -.
DR OrthoDB; 9815856at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000184608; Unassembled WGS sequence.
DR GO; GO:0046026; F:precorrin-4 C11-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11641; Precorrin-4_C11-MT; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR006362; Cbl_synth_CobM/CibF.
DR InterPro; IPR003043; Uropor_MeTrfase_CS.
DR NCBIfam; TIGR01465; cobM_cbiF; 1.
DR PANTHER; PTHR45790:SF4; COBALT-PRECORRIN-4 C(11)-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR45790; SIROHEME SYNTHASE-RELATED; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
DR PROSITE; PS00839; SUMT_1; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:SHI33988.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000184608};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SHI33988.1}.
FT DOMAIN 2..207
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 268 AA; 29051 MW; 5A1D479E1415E3C2 CRC64;
MTVYFIGAGP GDPDLITVKG AKLVETCPVV MYAGSLVPKA VIERAKPDAR IYDSASMDLD
QITQVYTEAH ANGEDVARVQ TGDLSIYSSL AEQTRRLDAL GIDWQVIPGV SSFQASAAAL
GQELTLPEAC QTIILSRASG RTPVPEKENL KSLASHEATL CLFLSATLIR KVVRELSEVY
PPHWPVCVVE KASHPQQRIL RGTLADIAEK MHAAGIRSTA MIIVSKVFAI DDFVDSKLYD
PTFSHACRKG RVVEENKDAG ADKTSLEN
//
