ID A0A1M6BBI0_9FLAO Unreviewed; 733 AA.
AC A0A1M6BBI0;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=SAMN04487911_102125 {ECO:0000313|EMBL:SHI45803.1};
OS Arenibacter nanhaiticus.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Arenibacter.
OX NCBI_TaxID=558155 {ECO:0000313|EMBL:SHI45803.1, ECO:0000313|Proteomes:UP000184231};
RN [1] {ECO:0000313|EMBL:SHI45803.1, ECO:0000313|Proteomes:UP000184231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.8863 {ECO:0000313|EMBL:SHI45803.1,
RC ECO:0000313|Proteomes:UP000184231};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; FQYX01000002; SHI45803.1; -; Genomic_DNA.
DR RefSeq; WP_072762946.1; NZ_FQYX01000002.1.
DR AlphaFoldDB; A0A1M6BBI0; -.
DR STRING; 558155.SAMN04487911_102125; -.
DR OrthoDB; 9763310at2; -.
DR Proteomes; UP000184231; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.10.1390; ATP-dependent DNA helicase RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR048671; RecQ-1-like_HTH.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01389; recQ; 1.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF21220; RecQ-1-like_HTH; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:SHI45803.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000184231}.
FT DOMAIN 7..358
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
FT DOMAIN 29..201
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 222..378
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 536..616
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 733 AA; 82475 MW; 9ED8641603F3FE5E CRC64;
MKLNEIDLRV SLKKYFGFSQ FKGLQEQVVK TILQGENTFV IMPTGGGKSL CYQLPALMQE
GTAIVVSPLI ALMKNQVDAI RGLSSEMGVA HVLNSSLTKT EIKQVKKDIS SGVTKLLYVA
PESLTKEEYV DFLQKEKISF VAVDEAHCIS EWGHDFRPEY RNLKAIVNRL GDNIPLIALT
ATATPKVQED IIKNLGINDA KIFLASFNRP NLYYEVRPKT QNVDSDIIRF VKQNSGKSGI
IYCLSRKRVE ELAQVLQVNG ISAVPYHAGF DAKTRSKHQD MFLMEDVDVV VATIAFGMGI
DKPDVRFVIH HDIPKSIESY YQETGRAGRD GGEGHCLAFY SYKDVEKLEK FMSGKPVAEQ
EIGNALLQEI VGYAETSISR RKFILHYFGE EFDEVNGEGA DMDDNTRNPK EKHEAKDNVV
KLISVVKGTS EKFKSKEIVK ALTGKVNALI ASHKTDEKEF FGIGKDRDKG YWMALIRQVL
VAGLLKKEIE QYGILHLTPK GEEFLENPTS FMMTRDHVYN KATDDAIVSA AKTAGGVADD
KLLRILKDLR KKQAQKLGVP PFVIFQDPSL EDMALKYPIS IEELVNIYGV GDGKAKKYGK
PFVAEIATYV EENDILRPDD LVVKSTGANS ALKLYIIQNV DRKLPLDDIA SAKGLELNEL
IKEMEQIVFS GTKLNIDYWI EEILDEDQQE EIHDYFLEAT TDDLKVALKE FDGDYEEEEL
RLYRLKFISE VAN
//
