ID   A0A1M6BNQ7_MALRU        Unreviewed;       789 AA.
AC   A0A1M6BNQ7;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Competence protein ComEC {ECO:0000313|EMBL:SHI50306.1};
GN   ORFNames=SAMN02745165_00247 {ECO:0000313|EMBL:SHI50306.1};
OS   Malonomonas rubra DSM 5091.
OC   Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Desulfuromonadales;
OC   Geopsychrobacteraceae; Malonomonas.
OX   NCBI_TaxID=1122189 {ECO:0000313|EMBL:SHI50306.1, ECO:0000313|Proteomes:UP000184171};
RN   [1] {ECO:0000313|EMBL:SHI50306.1, ECO:0000313|Proteomes:UP000184171}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5091 {ECO:0000313|EMBL:SHI50306.1,
RC   ECO:0000313|Proteomes:UP000184171};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FQZT01000001; SHI50306.1; -; Genomic_DNA.
DR   RefSeq; WP_072904927.1; NZ_FQZT01000001.1.
DR   AlphaFoldDB; A0A1M6BNQ7; -.
DR   STRING; 1122189.SAMN02745165_00247; -.
DR   OrthoDB; 9790149at2; -.
DR   Proteomes; UP000184171; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR   CDD; cd07731; ComA-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR035681; ComA-like_MBL.
DR   InterPro; IPR004477; ComEC_N.
DR   InterPro; IPR004797; Competence_ComEC/Rec2.
DR   InterPro; IPR025405; DUF4131.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   NCBIfam; TIGR00360; ComEC_N-term; 1.
DR   NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR   PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR   PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR   Pfam; PF03772; Competence; 1.
DR   Pfam; PF13567; DUF4131; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184171};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        27..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        240..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        286..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        388..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        415..437
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        444..464
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        484..501
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          541..738
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   789 AA;  88652 MW;  D2284DD9B6C3B8D9 CRC64;
     MLLIPALLFA TIAGLLLAPY AQLPKPIAIV VFACALLLGV FLRRRRFALL LFLLPIFFLQ
     ANLRYSLQFP LPLPVETFLE NKSRLLVKGD LLSVRQLTDQ RSQVDLEIFS LTDLDGAQLR
     PESCRLRLYV NEPLIGFLPG DKVAVEAKLR KPRLFGTPGE FHWPRYLAGQ GIALTGWVKK
     ADRIKLLGRS DRWVLSGITQ WRESAVEKLE RLTDETESVL LRALLLGEGK LLPDGVRKKL
     AAGGISHLFA ISGLHLGLLA LFGYQLLLTV YRRSPRLMNW QPPQRVLPIL LLPLLFLYLL
     VTGDAVSTRR AFFVATFAAL FWLCRYQVNP LRLLISLAFL SLLYNPLLLW QASWQLSFAG
     AAGILLWRPL WQGKTATLIP VLHWPLRLLL VTVSATLATQ SLVLANFHLL SPSGLLANLF
     AVPLVSLIAL PTGLLTLLVP GETFLHEMVI SLSAGILQII LLLIDYLTQL PGLNARYIFL
     NMREYWGIAF LLLLPLLWWQ LKNRRQKLLM TVSCCLLAAG CLWPQQRLNN LTLYMLSVGQ
     GESMLLVSPE GQSILIDGGG LYSDRFDVGE RLLAPALGEL GIDRLSAVLL THDHPDHRKG
     LLFVLRHFPV GQFWSAEEVD NLHPDLQRVL RETKTPVGKF SSGWTQVPGW MQEGLQLFHA
     KDSKNKNNSS LVLYLQDKSD GLLLTGDLEK QGVNRLLAAG LPGPVSLLKL PHHGSRYSNT
     RQLMRVTEPD IALVSAGYGN RYRFPAKELV DFSAEQKLPL YRTDTMGTIK AELSHERWKV
     TCWRDGLFR
//