ID   A0A1M6C6J5_9FIRM        Unreviewed;       385 AA.
AC   A0A1M6C6J5;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Homoaconitate hydratase {ECO:0000256|ARBA:ARBA00032706};
GN   ORFNames=SAMN02746098_04291 {ECO:0000313|EMBL:SHI56384.1};
OS   Desulfosporosinus lacus DSM 15449.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC   Desulfosporosinus.
OX   NCBI_TaxID=1121420 {ECO:0000313|EMBL:SHI56384.1, ECO:0000313|Proteomes:UP000183954};
RN   [1] {ECO:0000313|EMBL:SHI56384.1, ECO:0000313|Proteomes:UP000183954}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15449 {ECO:0000313|EMBL:SHI56384.1,
RC   ECO:0000313|Proteomes:UP000183954};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FQXJ01000020; SHI56384.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1M6C6J5; -.
DR   STRING; 1121420.SAMN02746098_04291; -.
DR   Proteomes; UP000183954; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:1901564; P:organonitrogen compound metabolic process; IEA:UniProt.
DR   GO; GO:0043436; P:oxoacid metabolic process; IEA:UniProt.
DR   Gene3D; 3.30.499.10; Aconitase, domain 3; 2.
DR   InterPro; IPR015931; Acnase/IPM_dHydase_lsu_aba_1/3.
DR   InterPro; IPR001030; Acoase/IPM_deHydtase_lsu_aba.
DR   InterPro; IPR036008; Aconitase_4Fe-4S_dom.
DR   PANTHER; PTHR43822:SF25; HOMOACONITASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43822; HOMOACONITASE, MITOCHONDRIAL-RELATED; 1.
DR   Pfam; PF00330; Aconitase; 2.
DR   SUPFAM; SSF53732; Aconitase iron-sulfur domain; 1.
PE   4: Predicted;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          26..224
FT                   /note="Aconitase/3-isopropylmalate dehydratase large
FT                   subunit alpha/beta/alpha"
FT                   /evidence="ECO:0000259|Pfam:PF00330"
FT   DOMAIN          258..383
FT                   /note="Aconitase/3-isopropylmalate dehydratase large
FT                   subunit alpha/beta/alpha"
FT                   /evidence="ECO:0000259|Pfam:PF00330"
SQ   SEQUENCE   385 AA;  40797 MW;  5210190B7F9BCE19 CRC64;
     MVDYFYKNLA RSAGLLEISQ GQDIEVDINL VLAHDGTGPK LLKLWNPEER VFDGRRVVFT
     VDHAFPAPTP QDRAFHKEFA VFSKVQGCTL YNKGEGVLHQ VVAERLSLCP GMIIAGADGH
     VATAGAFGAI AFALTPEELI PVMTTGKLRL KVPHVLSVQL DGELGPGILP RDVALYLSWK
     LGDQINGKAI ALSGALVNGL SDAGCMAICN FLPEAGAVTA FIVPPGEEGR PNFTLYAREI
     EAMIAVPPSP AEVRFVHELE GTTVTVAIAG GCSSGRVEDM EVIAEVLRDQ SVHPEVTFII
     TPASREVAKE MDNKGLSTLL RDRGALIMSP GCGPCPGKHF GVLAEGDVAI TTTVKNTPGR
     IGSTKASIYL ASPRTVAQAA VKGVI
//