ID   A0A1M6CNB2_9ACTN        Unreviewed;       276 AA.
AC   A0A1M6CNB2;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=2-amino-4,5-dihydroxy-6-oxo-7-(Phosphonooxy)heptanoate synthase {ECO:0000313|EMBL:SHI62198.1};
GN   ORFNames=SAMN05444521_8058 {ECO:0000313|EMBL:SHI62198.1};
OS   Streptomyces sp. 3214.6.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1882757 {ECO:0000313|EMBL:SHI62198.1, ECO:0000313|Proteomes:UP000190947};
RN   [1] {ECO:0000313|Proteomes:UP000190947}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3124.6 {ECO:0000313|Proteomes:UP000190947};
RA   Varghese N., Submissions S.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT670819; SHI62198.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1M6CNB2; -.
DR   STRING; 1882757.SAMN05444521_8058; -.
DR   OrthoDB; 9771504at2; -.
DR   Proteomes; UP000190947; Chromosome i.
DR   GO; GO:0004332; F:fructose-bisphosphate aldolase activity; IEA:InterPro.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002915; DeoC/FbaB/LacD_aldolase.
DR   InterPro; IPR041720; FbaB-like.
DR   PANTHER; PTHR47916:SF1; 3-HYDROXY-5-PHOSPHONOOXYPENTANE-2,4-DIONE THIOLASE-RELATED; 1.
DR   PANTHER; PTHR47916; FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 1; 1.
DR   Pfam; PF01791; DeoC; 1.
DR   PIRSF; PIRSF038992; Aldolase_Ia; 1.
DR   SMART; SM01133; DeoC; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000190947}.
FT   ACT_SITE        147
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR038992-1"
FT   ACT_SITE        178
FT                   /note="Schiff-base intermediate with dihydroxyacetone-P"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR038992-1"
SQ   SEQUENCE   276 AA;  28412 MW;  40519ADEE0E754A3 CRC64;
     MLKTGKLLRL RRLSLAGDGR HLFVPLDHSV SDGPIVPADK WDDLLRALVD GGADGIIVHK
     GRARAFAPDI LKHCALVVHL SASTACSADV HAKVLVADVE EALRLGADAV SVHVNIGSDT
     EAQQLADLGA VAGSCDAWGM PLIAMVYPRG PRIDDPRDPA LLAHVANVAA DLGADMVKTS
     VALPLERMAE VVANSPIPVL AAGGPPDDSD LVEYGTAVMA SGCRGLAVGR RIFSSPSPYA
     LVSRLSAVVH GGGGIAAEMS MTPTTSNYST IVAGVA
//