ID   A0A1M6CRX6_9FLAO        Unreviewed;      1254 AA.
AC   A0A1M6CRX6;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Cu(I)/Ag(I) efflux system membrane protein CusA/SilA {ECO:0000313|EMBL:SHI63601.1};
GN   ORFNames=SAMN04487911_10429 {ECO:0000313|EMBL:SHI63601.1};
OS   Arenibacter nanhaiticus.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Arenibacter.
OX   NCBI_TaxID=558155 {ECO:0000313|EMBL:SHI63601.1, ECO:0000313|Proteomes:UP000184231};
RN   [1] {ECO:0000313|EMBL:SHI63601.1, ECO:0000313|Proteomes:UP000184231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.8863 {ECO:0000313|EMBL:SHI63601.1,
RC   ECO:0000313|Proteomes:UP000184231};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FQYX01000004; SHI63601.1; -; Genomic_DNA.
DR   RefSeq; WP_072763272.1; NZ_FQYX01000004.1.
DR   AlphaFoldDB; A0A1M6CRX6; -.
DR   STRING; 558155.SAMN04487911_10429; -.
DR   OrthoDB; 9758757at2; -.
DR   Proteomes; UP000184231; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 4.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF19; CATION EFFLUX SYSTEM PROTEIN CUSA; 1.
DR   Pfam; PF00873; ACR_tran; 4.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184231};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        366..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        390..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        415..435
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        455..481
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        501..522
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        534..566
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        609..631
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        643..660
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1053..1072
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1078..1100
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1121..1140
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1205..1231
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1254 AA;  138806 MW;  7F8B667B3E8C05CD CRC64;
     MLNKSIKFLI QNKLVAVLLL VLFIGWGTMN APFNWDTGFL PNDPVAVDAI PDIGENQQIV
     FANWPGRSPQ DMEDQITYPL TSSLLGIPGV RTIRSTSMFG LSSIYIIFEE DVEFYWSRSR
     ILEKLNSLPS GLLPEGVSPS LGPDATGLGQ IFWYTLEGRD QNGEVTGGWD LHELRSVQDY
     YVKYGLSSAS GVAEVASIGG YVQEYQIDVD PELMKQYNIG LEQVVNAVKQ NNRDIGAQTL
     EINKAEYLVR GLGYIKSLED IKNAVVTAED YTPIRIMDIA KVALGPAERR GILDKEGAEV
     VGGVVVARYG ANPMEVINNV KAKIAEMGAG LPSKVLADGR TSQLTIVPFY DRTELIQETL
     GTLNEALSLE ILITIFVIIV MVFNLRASVL ISGLLPVAVL MVFIAMKFFG VDANIVALSG
     IAIAIGTMVD VGVILSENII RHMDENTKKL PVNTVVYNAT AEVSGAIVTA VMTTIISFIP
     VFTMIGAEGK LFRPLAFTKT AALSAALVVS LFLIPPFAAM LFKKRTIRTT VGYFLNALMA
     VLGVVALFFG YYLGVVLLAF AIVRFLKGQD KITDKQANLA NITVSVGTII TLLAQYWRPL
     GLDKNLSWNL LFVAIICFGL LGVFTLFRRY YVRILQWALQ NKLMFLSIPT LLVVFGFLIM
     KNTGKEFMPS LNEGSFLLMP TSMPHAGVEE NKRVLQQLDM AVASIPEIET VVGKSGRTDS
     ALDPAPLSMY ENIIQYKSEY MLNEQGERQR YKVNKDGYFI LRDGSMVVNP NSKHIDHDQH
     GPETPITAEI SRKQLIADDD GEYFRNWRPS IKSPNDIWNE IVAVTRLPGV TSAPKLQPIE
     TRLVMLQTGM RAPMGIKVKG QDLKQIEAFG MQLEAILKEA EGVKEEAVFA DRIVGKPYLL
     LDINREQLAR YGIMIEDVQR ILEVAVGGMT LTKTVEGRER YGVRVRYPRE LRGNPEELKN
     IYVPVAKGNP VPLSELVSVR YEQGPQMIKS EDTFLVGYVL FDKLDGFAEV AVVENAQALI
     LSKIESQELV VPKGISYQFT GTYENQLRAE KTLAIVVPLA LAIIFLILYF QFRSVATSFM
     VFSGIAVAFA GGFIMIWLYG QHWFLNFNFF GENLRDLFQM HTINLSVAVW VGFIALFGIA
     TDDGVVMATY LTQTFDRNNP MTKEGIWASV VEAGEKRIRP CLMTTATTIL ALLPVLTATG
     RGSDIMIPMA IPSFGGMLIA LITLFVVPVL YSSKAEIALK LKERNSANNL KLDE
//