ID   A0A1M6D6R6_9CLOT        Unreviewed;       378 AA.
AC   A0A1M6D6R6;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Radical SAM core domain-containing protein {ECO:0000259|Pfam:PF04055};
GN   ORFNames=SAMN02745176_01041 {ECO:0000313|EMBL:SHI68863.1};
OS   Lutispora thermophila DSM 19022.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Lutispora.
OX   NCBI_TaxID=1122184 {ECO:0000313|EMBL:SHI68863.1, ECO:0000313|Proteomes:UP000184442};
RN   [1] {ECO:0000313|EMBL:SHI68863.1, ECO:0000313|Proteomes:UP000184442}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19022 {ECO:0000313|EMBL:SHI68863.1,
RC   ECO:0000313|Proteomes:UP000184442};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FQZS01000006; SHI68863.1; -; Genomic_DNA.
DR   RefSeq; WP_073025170.1; NZ_FQZS01000006.1.
DR   AlphaFoldDB; A0A1M6D6R6; -.
DR   STRING; 1122184.SAMN02745176_01041; -.
DR   OrthoDB; 1674532at2; -.
DR   Proteomes; UP000184442; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd01335; Radical_SAM; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR007197; rSAM.
DR   PANTHER; PTHR42836; 7-CARBOXY-7-DEAZAGUANINE SYNTHASE; 1.
DR   PANTHER; PTHR42836:SF1; 7-CARBOXY-7-DEAZAGUANINE SYNTHASE; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SUPFAM; SSF102114; Radical SAM enzymes; 1.
PE   4: Predicted;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184442};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT   DOMAIN          91..206
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000259|Pfam:PF04055"
SQ   SEQUENCE   378 AA;  43904 MW;  CC97F9466C1B453E CRC64;
     MKISKKDALL WFDYFSQLTE KDEITAKHEE IIYATFAQIE TAVDYRNERL MEEIKGLKTL
     ENRTYFVGND DKFPKGCRSC LLGTGLSAIR KTNKCNLQCK FCYNYGEFER IPPVGEGMWE
     IGGTKFYEKD IDLLLSIHKK PTGISYVYLE PFMEIEKYYP VIKKFSEANI HQHLYTNGTL
     ATEENLKALG EAGLDEIRFN LGASNCSDKV IKNIGIAKKY IKSVGIETPM TPEFFDAFLK
     KKQAILDTKL DFINCAELHL NENNIFNYYG ENMYISRLGY ISPIWSRELT LKLMKIADEE
     CWDLVVHDCS NHTKFARDLN LSSKEGKWFG ASDYACEFLN IPYEVFIPIL NDDNFIFLKE
     EELPDEYKPV TMEEQMDF
//