ID   A0A1M6DGU1_BUTFI        Unreviewed;       186 AA.
AC   A0A1M6DGU1;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=Transcription repressor NadR {ECO:0008006|Google:ProtNLM};
GN   ORFNames=SAMN02745229_03517 {ECO:0000313|EMBL:SHI72208.1};
OS   Butyrivibrio fibrisolvens DSM 3071.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Butyrivibrio.
OX   NCBI_TaxID=1121131 {ECO:0000313|EMBL:SHI72208.1, ECO:0000313|Proteomes:UP000184278};
RN   [1] {ECO:0000313|EMBL:SHI72208.1, ECO:0000313|Proteomes:UP000184278}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 3071 {ECO:0000313|EMBL:SHI72208.1,
RC   ECO:0000313|Proteomes:UP000184278};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FQXK01000038; SHI72208.1; -; Genomic_DNA.
DR   RefSeq; WP_073389701.1; NZ_FQXK01000038.1.
DR   AlphaFoldDB; A0A1M6DGU1; -.
DR   STRING; 1121131.SAMN02745229_03517; -.
DR   GeneID; 40459041; -.
DR   OrthoDB; 9792661at2; -.
DR   Proteomes; UP000184278; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0036094; F:small molecule binding; IEA:InterPro.
DR   Gene3D; 3.30.1340.20; 3H domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR035922; 3H_dom_sf.
DR   InterPro; IPR004173; 3H_domain.
DR   InterPro; IPR013196; HTH_11.
DR   InterPro; IPR026043; NadR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR40068; TRANSCRIPTION REPRESSOR NIAR-RELATED; 1.
DR   PANTHER; PTHR40068:SF1; TRANSCRIPTION REPRESSOR NIAR-RELATED; 1.
DR   Pfam; PF02829; 3H; 1.
DR   Pfam; PF08279; HTH_11; 1.
DR   PIRSF; PIRSF037847; NiaR; 1.
DR   SUPFAM; SSF75500; Putative transcriptional regulator TM1602, C-terminal domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR037847-1};
KW   Nickel {ECO:0000256|PIRSR:PIRSR037847-1}.
FT   DOMAIN          8..61
FT                   /note="Helix-turn-helix type 11"
FT                   /evidence="ECO:0000259|Pfam:PF08279"
FT   DOMAIN          73..168
FT                   /note="3H"
FT                   /evidence="ECO:0000259|Pfam:PF02829"
FT   BINDING         76
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT   BINDING         84
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT   BINDING         143
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT   BINDING         145
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
SQ   SEQUENCE   186 AA;  20831 MW;  374D5C22EEB70809 CRC64;
     MRLSGEERRN NILEILAAAS EPISGSKLSK ELGVSRQVIV TDIALIKATH PDLVATNSGY
     ILMHASNTRR VYKVRHTNEQ IEDELSAIVD LGGSVQNVYV EHKVYGTITA PLQISSKRDI
     QNYLRDMRSG VSSPLSTITD GYHYHLIEAR SEAILDEIEE ALDKKGYLIE TQKAPVIYEP
     KYYSNI
//