ID A0A1M6DQR6_9FLAO Unreviewed; 367 AA.
AC A0A1M6DQR6;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Tyrosine lyase ThiH {ECO:0000313|EMBL:SHI75318.1};
GN ORFNames=SAMN04487911_10595 {ECO:0000313|EMBL:SHI75318.1};
OS Arenibacter nanhaiticus.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Arenibacter.
OX NCBI_TaxID=558155 {ECO:0000313|EMBL:SHI75318.1, ECO:0000313|Proteomes:UP000184231};
RN [1] {ECO:0000313|EMBL:SHI75318.1, ECO:0000313|Proteomes:UP000184231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.8863 {ECO:0000313|EMBL:SHI75318.1,
RC ECO:0000313|Proteomes:UP000184231};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; FQYX01000005; SHI75318.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M6DQR6; -.
DR STRING; 558155.SAMN04487911_10595; -.
DR OrthoDB; 9801120at2; -.
DR Proteomes; UP000184231; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR010722; BATS_dom.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR012726; ThiH.
DR InterPro; IPR034428; ThiH/NoCL/HydG-like.
DR NCBIfam; TIGR02351; thiH; 1.
DR PANTHER; PTHR43583; 2-IMINOACETATE SYNTHASE; 1.
DR PANTHER; PTHR43583:SF1; 2-IMINOACETATE SYNTHASE; 1.
DR Pfam; PF06968; BATS; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDF00301; 2-iminoacetate_synthase_(ThiH); 1.
DR SFLD; SFLDG01060; BATS_domain_containing; 1.
DR SMART; SM00876; BATS; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lyase {ECO:0000313|EMBL:SHI75318.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000184231};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 69..313
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 367 AA; 42209 MW; 013938EB97256281 CRC64;
MFQDLFDTYN WDETLKSIYA KTAKDVRNAL DNPNRDLEDF KALISPAAAP FLEEMAQISR
MLTKKRFGNT IQMYSPMYLS NECQNICTYC GFSLTNKIPR RTLTDKEILQ EVDYIKSKGY
DHILLVTGEA NTTVGVAYID NAIQLIRSHF SNITIEVQPL EQEDYELLKG SGLYAVLVYQ
ETYHRDEYKK HHPKGKKSNF DYRLATPDRL GKAGVHKIGL GALFGLEDWR ADSFFTALHL
KYLQKTYWKT KYSISFPRLR PHSGGLEPKV AMTDPHLVQL ICAYRLLDED VELSISTRES
EIFRNHIVNL GITSISAESK TNPGGYTVEK QSLEQFEISD ERSTEAVAEM LKAQGLEVVW
KDWEHYL
//
