ID   A0A1M6E4M9_9BACE        Unreviewed;       871 AA.
AC   A0A1M6E4M9;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=SAMN05444350_10892 {ECO:0000313|EMBL:SHI80218.1};
OS   Bacteroides stercorirosoris.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=871324 {ECO:0000313|EMBL:SHI80218.1, ECO:0000313|Proteomes:UP000184192};
RN   [1] {ECO:0000313|EMBL:SHI80218.1, ECO:0000313|Proteomes:UP000184192}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 26884 {ECO:0000313|EMBL:SHI80218.1,
RC   ECO:0000313|Proteomes:UP000184192};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR   EMBL; FQZN01000008; SHI80218.1; -; Genomic_DNA.
DR   RefSeq; WP_025832264.1; NZ_FQZN01000008.1.
DR   AlphaFoldDB; A0A1M6E4M9; -.
DR   eggNOG; COG0210; Bacteria.
DR   Proteomes; UP000184192; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF63; DNA HELICASE IV; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          156..630
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         177..184
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   871 AA;  100981 MW;  BFF7785B3DB2D46F CRC64;
     MQLLFIMMIC IIAISVIVIA MVRIRLKNKS NELSDKLSQI SSYSEKSNYE QAKERLSALN
     EKVFIDIPTN LNNGFYGNII SATQEKDFIN HYKPHFQEAY SLQKKLKAFN ITPSETILKF
     INDFGAINRL VKQHNEGVIA FLLDTHKDFF DKCLKYPLDK QQRRSIVSEE DNCLVVSSAG
     SGKTSSIIGK VKYLTEIKGI APHRILLISY TNKAAAELTE RMATDGLKGY TFHKLAIDII
     GKATGTKPFI CDNTDSLFIA LYHTLLENKA FKNSVVEYFI DYQTNEADWE QRKNERREKL
     SEQKNVQLKA MFPDMDGRAI YVRSEQEQKI CFVLSSLGVK FRYEEPYEHQ LADEMHSQYR
     PDFSIYFEQT GEIKRIYLEH FGVDEHGLVP AWFAKDKNIT YEEANQKYND GITWKKAAHE
     KFGTQLLVTS SADFHYSDIR DKLRQLLNDA GVPIQEKTEE ELYDLVLPKG SKQEKAFIRL
     VVTFVTLVKS SCKSVREVLE QAKNANDERS VFIIKNIFQP VYDRYISALS DSNQIDFTDA
     ILQATEICRT SHPVEYDYII VDEFQDISVD RYNFLKVLRE GNPPAKLYCV GDDWQSIYRF
     SGSDMALFNQ FPEYFGATEI NKIETTYRFG EPLVSLSSHF IQRNKAQIQK NIHSFSSEMK
     TELEFYSYDR RDYCKTIGEL ISSIPSDKSI FLLGRYSFDD YYLSFMYKGV KEGNRFYYVI
     GGRKIEFSTV HKSKGLEADY VILLQCNKDT YGFPSLVSDD PVLNYVLTKS DQFPYGEERR
     LFYVAVTRAK IKTLVLYDKR FPSVFVDEFL HPEKVSEESY VKHPNANKRW TRSADQFLLK
     LYNEGKSVKY IANKMGRSQT SIVMRLNKLT Q
//