ID   A0A1M6G4V0_MALRU        Unreviewed;       690 AA.
AC   A0A1M6G4V0;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=HD-GYP domain, c-di-GMP phosphodiesterase class II (Or its inactivated variant) {ECO:0000313|EMBL:SHJ04999.1};
GN   ORFNames=SAMN02745165_01411 {ECO:0000313|EMBL:SHJ04999.1};
OS   Malonomonas rubra DSM 5091.
OC   Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Desulfuromonadales;
OC   Geopsychrobacteraceae; Malonomonas.
OX   NCBI_TaxID=1122189 {ECO:0000313|EMBL:SHJ04999.1, ECO:0000313|Proteomes:UP000184171};
RN   [1] {ECO:0000313|EMBL:SHJ04999.1, ECO:0000313|Proteomes:UP000184171}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5091 {ECO:0000313|EMBL:SHJ04999.1,
RC   ECO:0000313|Proteomes:UP000184171};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FQZT01000004; SHJ04999.1; -; Genomic_DNA.
DR   RefSeq; WP_072907215.1; NZ_FQZT01000004.1.
DR   AlphaFoldDB; A0A1M6G4V0; -.
DR   STRING; 1122189.SAMN02745165_01411; -.
DR   OrthoDB; 9769359at2; -.
DR   Proteomes; UP000184171; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR   PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF13487; HD_5; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00471; HDc; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS51831; HD; 1.
DR   PROSITE; PS51832; HD_GYP; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000184171}.
FT   DOMAIN          284..336
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          497..690
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
FT   DOMAIN          519..641
FT                   /note="HD"
FT                   /evidence="ECO:0000259|PROSITE:PS51831"
SQ   SEQUENCE   690 AA;  77002 MW;  9A1F66BC3A7FAC9B CRC64;
     MKYLPQLKSR VSRRIFLAVL LCALVPISGL ILLTLQSVRA NLEADTARRL HHAGKNIGMA
     VVTEFVSVES ALKKIASLYD VPGNGLELEE NFGEALLEKF WLQPAGAHFP IAGLNFSEEY
     KDRLASGSSQ LVLARVNQAI TLYLCIPTTD AHSKPVIAVG KISLPALEEY ALNFLPLNAQ
     LILLDADWQP LTGNLSNMLA PDQFHKKGES GHSYAEIHQA GETWLAGRWS LFLKAAFNTS
     NWNILVLEPK AEIFSSLAHF GRNAWLTSAM AFWVILLTSS ILVRKTLQPL QQLKEATREI
     GQGHFNCQVR LDSRDEFEEL STSFNQMTTK IQQQVQQQQD MGQAVRQILG AIDMEAIIVN
     FLRNIRVFES ISTLSLTLYN EMEQNSSATW LSSRTEKSGI ELLSNAVIAA DEVELLLHEK
     EACSVPQWRF PTLLQPLAER GGKLFSLLLI EYKPSMHAIV GLSHASEQAE QSDLLIARQL
     ADQLRVALSR AEMVKELDDL NLGILTALAR TVDANSQWTH GHSERVTEYA FQIAKAMGQD
     ESACLDLHQA GLLHDLGKVA VPAEILNKPG KLTDEEFEII KRHPVEAVRI IEPIQVFGKI
     LPIVRQHHER WDGTGYPDGL KGTEIHLGAR ILAVADVYDA LYSERPYRAS WNQEKVLAYL
     QGQAGKAFDP EVVNAFCTLV QQDDRWRNCS
//