ID A0A1M6J4F2_9FLAO Unreviewed; 428 AA.
AC A0A1M6J4F2;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Hemolysin, contains CBS domains {ECO:0000313|EMBL:SHJ41542.1};
GN ORFNames=SAMN04488007_0262 {ECO:0000313|EMBL:SHJ41542.1};
OS Maribacter aquivivus.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Maribacter.
OX NCBI_TaxID=228958 {ECO:0000313|EMBL:SHJ41542.1, ECO:0000313|Proteomes:UP000184314};
RN [1] {ECO:0000313|EMBL:SHJ41542.1, ECO:0000313|Proteomes:UP000184314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16478 {ECO:0000313|EMBL:SHJ41542.1,
RC ECO:0000313|Proteomes:UP000184314};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FQZX01000001; SHJ41542.1; -; Genomic_DNA.
DR RefSeq; WP_073240563.1; NZ_FQZX01000001.1.
DR AlphaFoldDB; A0A1M6J4F2; -.
DR STRING; 228958.SAMN04488007_0262; -.
DR OrthoDB; 9798188at2; -.
DR Proteomes; UP000184314; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF33; UPF0053 PROTEIN YEGH; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01595; CNNM; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..200
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 278..338
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 428 AA; 48442 MW; A0605AE29C752463 CRC64;
MGTAGIIIIL SLIFSAFFSG MEIAFISANK IHIEIEKKQD GFLARVLTRL TKKPSKFIAT
MLIGNNIALV IYGLFMGDVL MNWFTGIVPD NALLKLLITD FSLLTQTLIS TFVILITAEF
LPKVLFQIYA NNLLKLLAIP AFLFYILFSF ISDFIIWISD LILKYVFGTS GDEVQLAFSK
LELGDYITEQ METIEEEDEV DTEIQIFQNA LEFAAVKARE VMVPRTEIVA VEMYESPKNL
AKIFTETGYS KILVFNDTVD NVIGYVHSYE LFKKPKTIKS ILLPVEFVPE TMLIQDILNV
LIKKRKSIAV VLDEYGGTSG LVTVEDIVEE LFGEIEDEHD TTDLREEVVD ERHFLFSARL
EVDDINENHK LNLPVSDEYE TLGGLLVHTL GEIPDKEVEL TIASYKFTVL EVSNTKIDLI
SIEVLEEE
//
