ID   A0A1M6J684_9RHOB        Unreviewed;       212 AA.
AC   A0A1M6J684;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Chloramphenicol acetyltransferase {ECO:0000256|ARBA:ARBA00020291};
DE            EC=2.3.1.28 {ECO:0000256|ARBA:ARBA00013235};
GN   ORFNames=SAMN05444000_108118 {ECO:0000313|EMBL:SHJ42157.1};
OS   Shimia gijangensis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae.
OX   NCBI_TaxID=1470563 {ECO:0000313|EMBL:SHJ42157.1, ECO:0000313|Proteomes:UP000183982};
RN   [1] {ECO:0000313|Proteomes:UP000183982}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 100564 {ECO:0000313|Proteomes:UP000183982};
RA   Varghese N., Submissions S.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetyl-CoA + chloramphenicol = chloramphenicol 3-acetate +
CC         CoA; Xref=Rhea:RHEA:18421, ChEBI:CHEBI:16730, ChEBI:CHEBI:17698,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=2.3.1.28;
CC         Evidence={ECO:0000256|ARBA:ARBA00036833};
CC   -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC       {ECO:0000256|ARBA:ARBA00007274}.
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DR   EMBL; FQZQ01000008; SHJ42157.1; -; Genomic_DNA.
DR   RefSeq; WP_073251783.1; NZ_FQZQ01000008.1.
DR   AlphaFoldDB; A0A1M6J684; -.
DR   STRING; 1470563.SAMN05444000_108118; -.
DR   OrthoDB; 9815592at2; -.
DR   Proteomes; UP000183982; Unassembled WGS sequence.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   CDD; cd03349; LbH_XAT; 1.
DR   Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR018357; Hexapep_transf_CS.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   PANTHER; PTHR43300; ACETYLTRANSFERASE; 1.
DR   PANTHER; PTHR43300:SF12; CHLORAMPHENICOL ACETYLTRANSFERASE; 1.
DR   Pfam; PF00132; Hexapep; 1.
DR   SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
DR   PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW   Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW   Reference proteome {ECO:0000313|Proteomes:UP000183982};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SHJ42157.1}.
SQ   SEQUENCE   212 AA;  23473 MW;  61364C7EF4D28C19 CRC64;
     MDNYFESPFR GVTLDKQVTN PNIIVDRYSY YSGYYHGHSF DGCARYLSPD DGADQLHIGS
     FCSIGSGAAF IMAGNQGHRN DWTSTFPFHY WMDEEPAFAD ATNGYQPAGN TVIGNDVWIG
     SEAIILPGVG IGDGAVIGTR ALVSRDVEPY TIVGGNPAKT IRKRFDDRLI GLLLEMKWWD
     WPEDQLTAAM PLLTSGQIEE LHGLWIANIK TC
//