ID A0A1M6KDB6_9BURK Unreviewed; 432 AA.
AC A0A1M6KDB6;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=L-fuconate dehydratase {ECO:0000256|ARBA:ARBA00013142};
DE EC=4.2.1.68 {ECO:0000256|ARBA:ARBA00013142};
GN ORFNames=SAMN05192548_1003183 {ECO:0000313|EMBL:SHJ56857.1};
OS Paraburkholderia terricola.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=169427 {ECO:0000313|EMBL:SHJ56857.1, ECO:0000313|Proteomes:UP000184395};
RN [1] {ECO:0000313|EMBL:SHJ56857.1, ECO:0000313|Proteomes:UP000184395}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 20594 {ECO:0000313|EMBL:SHJ56857.1,
RC ECO:0000313|Proteomes:UP000184395};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H2O;
CC Xref=Rhea:RHEA:22772, ChEBI:CHEBI:15377, ChEBI:CHEBI:21291,
CC ChEBI:CHEBI:37448; EC=4.2.1.68;
CC Evidence={ECO:0000256|ARBA:ARBA00001737};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; FRAB01000003; SHJ56857.1; -; Genomic_DNA.
DR RefSeq; WP_073427404.1; NZ_JAVDRP010000001.1.
DR AlphaFoldDB; A0A1M6KDB6; -.
DR STRING; 169427.SAMN05192548_1003183; -.
DR KEGG; pts:CUJ90_27840; -.
DR OrthoDB; 8609034at2; -.
DR Proteomes; UP000184395; Unassembled WGS sequence.
DR GO; GO:0050023; F:L-fuconate dehydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0009063; P:amino acid catabolic process; IEA:InterPro.
DR GO; GO:0016052; P:carbohydrate catabolic process; IEA:InterPro.
DR CDD; cd03324; rTSbeta_L-fuconate_dehydratase; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR034610; L-fuconate_dehydratase.
DR InterPro; IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR013341; Mandelate_racemase_N_dom.
DR InterPro; IPR046945; RHMD-like.
DR PANTHER; PTHR13794; ENOLASE SUPERFAMILY, MANDELATE RACEMASE; 1.
DR PANTHER; PTHR13794:SF58; MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF02746; MR_MLE_N; 1.
DR SFLD; SFLDF00111; L-fuconate_dehydratase; 1.
DR SFLD; SFLDG00179; mandelate_racemase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR PROSITE; PS00909; MR_MLE_2; 1.
PE 4: Predicted;
FT DOMAIN 199..295
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
SQ SEQUENCE 432 AA; 48259 MW; A38981790458C2ED CRC64;
MTTITNLSVR DIRFPTSRSL DGSDAMNAAP DYSAAYVVLE TDSPEQFAGH GLTFTIGRGN
EICVTAVNAL APLVVGKTLE AIVADMGSFW RAFTSDSQLR WIGPDKGAIH LATAAVVNAV
WDLWAKTERK PVWKLLVDMS PEALVRCLDF RYVTDALTPH EALAILRRHA ATRGEREAQM
LAHGYPAYTT SAGWLGYDDE KIRRLAREGV AQGWTHFKQK VGGNLDEDVR RARILRDEIG
ADRKLMMDAN QVWEVDEAIA NMRRLAEFDP WWIEEPTSPD DILGHAAIRR RVAPIGVATG
EHCHNRVMFK QLLQAQAIDF CQVDSCRLGG LNEVLVVLLM AAKFGVPVCP HAGGVGLCEY
VQHISLFDYI CVSASLENRV LEYVDHLHEH FVDPVVIRNG RYMPPQQPGY SIEMRAESLE
QFHFPQGAAW RV
//
