ID A0A1M6LPJ9_9CLOT Unreviewed; 562 AA.
AC A0A1M6LPJ9;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:SHJ73145.1};
GN ORFNames=SAMN02745883_00294 {ECO:0000313|EMBL:SHJ73145.1};
OS Caminicella sporogenes DSM 14501.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Caminicella.
OX NCBI_TaxID=1121266 {ECO:0000313|EMBL:SHJ73145.1, ECO:0000313|Proteomes:UP000184082};
RN [1] {ECO:0000313|EMBL:SHJ73145.1, ECO:0000313|Proteomes:UP000184082}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14501 {ECO:0000313|EMBL:SHJ73145.1,
RC ECO:0000313|Proteomes:UP000184082};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; FRAJ01000003; SHJ73145.1; -; Genomic_DNA.
DR RefSeq; WP_072965603.1; NZ_FRAJ01000003.1.
DR AlphaFoldDB; A0A1M6LPJ9; -.
DR SMR; A0A1M6LPJ9; -.
DR STRING; 1121266.SAMN02745883_00294; -.
DR Proteomes; UP000184082; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000184082};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..206
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 247..554
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 562 AA; 62738 MW; EC6E5EECBAEAFFFC CRC64;
MSVKDNKDKS EKGLKKLRKR LTIMFTLVTV ILICLIGRLC YIQIIKGNDL RQMAVKQWSE
TVSIVDKRGK IYDRNYIPLT SRVKEDYIII HPSIKLNDKV LNLLSISTKL DVETLKKVLS
KKDRYKKLLI KYYDIDILRE LLSMGIQTVE ITKRYDGSKL ASHIIGYIKE SENAGMSGLE
KYFDTELTKD RGTVISVVKD AKNRIIPGFG YAVYKEDDNK KENIVTTIDY NIQKISEKEF
DKYNFDGSVV VLDSKSGDIL AMVSRPNFDP DNVANYLNSN NMELYNKAVQ ISFPPGSIFK
IIVAAAAIEK KLVDMQQNFY CKGYEKLGKD IIIKCHSYEK GGHGNLNLKQ AFAASCNSVF
IQIGQILGGE EILNMAKKFG LGKKTGIKID KETEGVLPTE DYVKGAGIGN ISIGQGCLEV
TPLQVAKFTN IIANNGVDVG VRLVKEIISD NGKIKKKFKK DSINRVISSD TAQKIKDMMI
QTVEEGTGRS AKIDDIEVAG KTGSAETVVG GQKTVHAWFT GFFDGKKSRY VITIIAERKG
SGGKFAAPIF KNIAKRLIEM GY
//
