ID   A0A1M6MUG4_9FIRM        Unreviewed;       512 AA.
AC   A0A1M6MUG4;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=PTS system, maltose and glucose-specific IIC component {ECO:0000313|EMBL:SHJ87111.1};
GN   ORFNames=SAMN02745227_00900 {ECO:0000313|EMBL:SHJ87111.1};
OS   Anaerobranca californiensis DSM 14826.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Proteinivoraceae;
OC   Anaerobranca.
OX   NCBI_TaxID=1120989 {ECO:0000313|EMBL:SHJ87111.1, ECO:0000313|Proteomes:UP000243547};
RN   [1] {ECO:0000313|Proteomes:UP000243547}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14826 {ECO:0000313|Proteomes:UP000243547};
RA   Varghese N., Submissions S.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FRAI01000008; SHJ87111.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1M6MUG4; -.
DR   STRING; 1120989.SAMN02745227_00900; -.
DR   Proteomes; UP000243547; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd00212; PTS_IIB_glc; 1.
DR   Gene3D; 3.30.1360.60; Glucose permease domain IIB; 1.
DR   InterPro; IPR036878; Glu_permease_IIB.
DR   InterPro; IPR018113; PTrfase_EIIB_Cys.
DR   InterPro; IPR003352; PTS_EIIC.
DR   InterPro; IPR013013; PTS_EIIC_1.
DR   InterPro; IPR001996; PTS_IIB_1.
DR   NCBIfam; TIGR00826; EIIB_glc; 1.
DR   PANTHER; PTHR30009; CYTOCHROME C-TYPE SYNTHESIS PROTEIN AND PTS TRANSMEMBRANE COMPONENT; 1.
DR   PANTHER; PTHR30009:SF24; PTS SYSTEM, IIBC COMPONENT; 1.
DR   Pfam; PF00367; PTS_EIIB; 1.
DR   Pfam; PF02378; PTS_EIIC; 1.
DR   SUPFAM; SSF55604; Glucose permease domain IIB; 1.
DR   PROSITE; PS51098; PTS_EIIB_TYPE_1; 1.
DR   PROSITE; PS01035; PTS_EIIB_TYPE_1_CYS; 1.
DR   PROSITE; PS51103; PTS_EIIC_TYPE_1; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW   Reference proteome {ECO:0000313|Proteomes:UP000243547};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        59..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        90..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        129..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        167..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        193..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        276..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        308..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        383..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          3..417
FT                   /note="PTS EIIC type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS51103"
FT   DOMAIN          434..512
FT                   /note="PTS EIIB type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS51098"
FT   ACT_SITE        456
FT                   /note="Phosphocysteine intermediate; for EIIB activity"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00421"
SQ   SEQUENCE   512 AA;  55481 MW;  161650EE88C5C701 CRC64;
     MKQNLKDFFQ QLGRSFMLPI SLLAATGIFL GLAAASANPQ IQQVVPFLAS SSVMYVTQLI
     RAISGTLLGN IPLLFAISLS LGMAKKEKPI AAFAGVIVFL VFNRSMMYVL DNTSLQLDAV
     GNVLGMNTVR MDALGGILVG LITAMIHNKY YNIKLPDAIA FFGGTRFVAI AVTVVFAVLG
     QIIPFIWEPI SAIITGVGTS IAQLGYFGTF LFGFLERVLL PFGLHHILNS LARTTEIGGV
     AEFAGETVTG ALLIFNRYLE TGVTPDNLPL TEVTRFLAQG KIPMMVFGLP AAAYAMYKTA
     DPAKRAKVKP LLLAGVLASF TTGITEPLEF AFLFVAPMSY LFHAVMAGIS FMSMHLLGVM
     IGNTQGGIID LLVFGATQPG SKWYMAIIVG VLFAVVYYNV FKWAIIKFNF ATPGREENGE
     NEDVLGDVSN KELEGLALQI IEGLGGKENI VALENCFTRL RVDVVDMTKV DERKIEKTGA
     NGFIKPNPKH IQIIYGPKVN IIKDVVEGKL NM
//