ID   A0A1M6MZA3_9FLAO        Unreviewed;       487 AA.
AC   A0A1M6MZA3;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Methylmalonate-semialdehyde dehydrogenase [acylating] {ECO:0000313|EMBL:SHJ88653.1};
GN   ORFNames=SAMN05444371_0058 {ECO:0000313|EMBL:SHJ88653.1};
OS   Epilithonimonas mollis.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC   Chryseobacterium group; Epilithonimonas.
OX   NCBI_TaxID=216903 {ECO:0000313|EMBL:SHJ88653.1, ECO:0000313|Proteomes:UP000184498};
RN   [1] {ECO:0000313|Proteomes:UP000184498}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18016 {ECO:0000313|Proteomes:UP000184498};
RA   Varghese N., Submissions S.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FRAM01000001; SHJ88653.1; -; Genomic_DNA.
DR   RefSeq; WP_072995681.1; NZ_FRAM01000001.1.
DR   AlphaFoldDB; A0A1M6MZA3; -.
DR   STRING; 216903.SAMN05444371_0058; -.
DR   OrthoDB; 629320at2; -.
DR   Proteomes; UP000184498; Unassembled WGS sequence.
DR   GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity; IEA:InterPro.
DR   CDD; cd07085; ALDH_F6_MMSDH; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR010061; MeMal-semiAld_DH.
DR   NCBIfam; TIGR01722; MMSDH; 1.
DR   PANTHER; PTHR43866; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR43866:SF4; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          22..472
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
SQ   SEQUENCE   487 AA;  52890 MW;  AFE71155FCF79B38 CRC64;
     MSNKYGKAKN YINGRLVETM TDRWMPVESP LTGEVIAEVA VSSKEDLDKA VSAAKEAFKT
     WSKTPIKDRV QVFFRYKTLL EQNMAELSAL IQEENGKTLD EARAEIEKSI ELTEFAVSLP
     QLTQGEILEV SKGVECRTEH SALGVVASIV PFNFPSMVPN WTIPNAIALG NTMILKTSEL
     VPLSALKIAD LLKQAGLPDG VLNIVHGEKE IVEAICDHPD IEAVSFVGST KVAKIVYQRA
     TSNLKRCLAL GGAKNHLLVL PDANPEMTAA NVTASMSGCA GQRCMAASAM VAVGQTDHII
     EKMVQEARNV VPGKNLGSVI SKAAKERIEG YITQAEKDGA KILLDGRNYQ VEGKENGYYV
     GPTIIDFVTP EMSVAREEIF GPVISIIRSR SLEEAMKIEN ANPYGNAASV FTQSGGLARY
     VMENASAGMI GVNIGVPVPR EPFSFGGWNE SRFGVGDITG KSSIEFWTKL KKMTTKWNPE
     AGINWMS
//