ID   A0A1M6N7S6_PSETH        Unreviewed;       316 AA.
AC   A0A1M6N7S6;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=5'-3' exonuclease {ECO:0000313|EMBL:SHJ91586.1};
GN   ORFNames=SAMN05443637_10174 {ECO:0000313|EMBL:SHJ91586.1};
OS   Pseudonocardia thermophila.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Pseudonocardia.
OX   NCBI_TaxID=1848 {ECO:0000313|EMBL:SHJ91586.1, ECO:0000313|Proteomes:UP000184363};
RN   [1] {ECO:0000313|EMBL:SHJ91586.1, ECO:0000313|Proteomes:UP000184363}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43832 {ECO:0000313|EMBL:SHJ91586.1,
RC   ECO:0000313|Proteomes:UP000184363};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FRAP01000001; SHJ91586.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1M6N7S6; -.
DR   STRING; 1848.SAMN05443637_10174; -.
DR   OrthoDB; 9806424at2; -.
DR   Proteomes; UP000184363; Unassembled WGS sequence.
DR   GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR   CDD; cd09898; H3TH_53EXO; 1.
DR   CDD; cd09859; PIN_53EXO; 1.
DR   Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR   InterPro; IPR002421; 5-3_exonuclease.
DR   InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR   InterPro; IPR020045; DNA_polI_H3TH.
DR   InterPro; IPR038969; FEN.
DR   InterPro; IPR008918; HhH2.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR   PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR   Pfam; PF01367; 5_3_exonuc; 1.
DR   Pfam; PF02739; 5_3_exonuc_N; 1.
DR   SMART; SM00475; 53EXOc; 1.
DR   SMART; SM00279; HhH2; 1.
DR   SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Exonuclease {ECO:0000313|EMBL:SHJ91586.1};
KW   Hydrolase {ECO:0000313|EMBL:SHJ91586.1};
KW   Nuclease {ECO:0000313|EMBL:SHJ91586.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184363}.
FT   DOMAIN          1..281
FT                   /note="5'-3' exonuclease"
FT                   /evidence="ECO:0000259|SMART:SM00475"
SQ   SEQUENCE   316 AA;  33553 MW;  73691D05CA4FFA9C CRC64;
     MLLDAASMYF RAFYGVPESI TAPDGTPVNA VRGFTDMVAR LINDHRPARL VACLDLDWRP
     AFRVNALPTY KAHRVPGEPE TAPPGVPEEV PDALAPQVPV LLQVLAAAGI ATAGAEGYEA
     DDVIGTLAAR ERTHPVLAVS GDRDLMQIVT DDDPGVRLLY VGRGLAKAEL LGPAEVAEKY
     GVPRARAGEA YAEMAMLRGD PSDGLPGVPG IGAKTAATIV GRYDTWAKLL AAVSDPSDTR
     MSPNVRTKLA KAADYLAVVE PVVRVARDAD VVLDRDDTLP VEPADGAKLL ELVERWGIGG
     SVERLLQALQ NAARSR
//