ID A0A1M6NE71_9FIRM Unreviewed; 677 AA.
AC A0A1M6NE71;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN ORFNames=SAMN02745136_01274 {ECO:0000313|EMBL:SHJ94038.1};
OS Anaerocolumna jejuensis DSM 15929.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Anaerocolumna.
OX NCBI_TaxID=1121322 {ECO:0000313|EMBL:SHJ94038.1, ECO:0000313|Proteomes:UP000184386};
RN [1] {ECO:0000313|EMBL:SHJ94038.1, ECO:0000313|Proteomes:UP000184386}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15929 {ECO:0000313|EMBL:SHJ94038.1,
RC ECO:0000313|Proteomes:UP000184386};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
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DR EMBL; FRAC01000008; SHJ94038.1; -; Genomic_DNA.
DR RefSeq; WP_073274038.1; NZ_FRAC01000008.1.
DR AlphaFoldDB; A0A1M6NE71; -.
DR STRING; 1121322.SAMN02745136_01274; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000184386; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:SHJ94038.1};
KW Cilium {ECO:0000313|EMBL:SHJ94038.1};
KW Flagellum {ECO:0000313|EMBL:SHJ94038.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000184386};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 30..48
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 60..81
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 101..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 189..210
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 230..250
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 270..301
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 677 AA; 74383 MW; F55F76023B882D8D CRC64;
MKKTDMVVGI YLLAAIIFLI VPIPSVLLDI LLALNISVAL IVLFNALFSR EALNMSAFPT
ILLFTTIFRI SLNVSSMRLI LRDGFAGGVI QTFGNFVGGG DAIIGIIVFV ILILVQFIVI
NKGSERVAEV TARFTLDAMP GKQMAIDADL NTGAISDVQA KERREKIQEE ASFFGAMDGA
TKYVKGDAIA GLIIVIINFV GGIAIGAFRG GMSINEAFDK YTLLTIGEGL VSQIPSLLIS
LSTGIVVTKA TKEADIGDTL LKQLFSIPKV LYIVGGALIF LGIATPLNTL VFCTYGVVFI
ICGRTIAGRI EVEDIESAAA MEESGGDEIR KPENVVTLLQ VDPIELEFGY GIIPLADVNQ
GGDLLDRVVL IRRQIALELG CVVPIIRLRD NIQLNPNQYL IKIKGVPISE GEILFDHYMA
MNPGYVEEEI TGIPTFEPSF HLPAIWITES QRERAESLGY TVVDPPSIIA THLTEVIRSH
IYELLTRQDV QNLINNIQEA NGTLVQELVP KLLSVGEIQK VLQNLLKEGI SIRDLITIFE
TLADYASTTR DTDVLTEYAR QSLKRAISNK YFPVEEVTSV VTLDPKVEQD IMNSVKQTEQ
GAYLTLDPEK TRSIMSSVEE EVQKLENIGK SPIVITSPIV RMYFKKLTQD YFKDLIVISY
NEIESNVELQ SVGMVTV
//
