ID A0A1M6P6Q7_9CLOT Unreviewed; 457 AA.
AC A0A1M6P6Q7;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Alanine or glycine:cation symporter, AGCS family {ECO:0000313|EMBL:SHK03572.1};
GN ORFNames=SAMN02745248_01608 {ECO:0000313|EMBL:SHK03572.1};
OS Hathewaya proteolytica DSM 3090.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Hathewaya.
OX NCBI_TaxID=1121331 {ECO:0000313|EMBL:SHK03572.1, ECO:0000313|Proteomes:UP000183952};
RN [1] {ECO:0000313|EMBL:SHK03572.1, ECO:0000313|Proteomes:UP000183952}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3090 {ECO:0000313|EMBL:SHK03572.1,
RC ECO:0000313|Proteomes:UP000183952};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC ECO:0000256|RuleBase:RU363064}.
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DR EMBL; FRAD01000012; SHK03572.1; -; Genomic_DNA.
DR RefSeq; WP_072903565.1; NZ_FRAD01000012.1.
DR AlphaFoldDB; A0A1M6P6Q7; -.
DR STRING; 1121331.SAMN02745248_01608; -.
DR OrthoDB; 9804874at2; -.
DR Proteomes; UP000183952; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR001463; Na/Ala_symport.
DR NCBIfam; TIGR00835; agcS; 1.
DR PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR PANTHER; PTHR30330:SF14; SODIUM_AMINO ACID (ALANINE) SYMPORTER-RELATED; 1.
DR Pfam; PF01235; Na_Ala_symp; 1.
DR PRINTS; PR00175; NAALASMPORT.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU363064};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW Reference proteome {ECO:0000313|Proteomes:UP000183952};
KW Symport {ECO:0000256|RuleBase:RU363064};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363064};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363064};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 68..92
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 98..119
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 182..201
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 213..233
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 239..262
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 312..331
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 351..375
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 387..407
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 419..436
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
SQ SEQUENCE 457 AA; 48958 MW; BF6781CD99FF8995 CRC64;
MAILGQFITT VSDFLWNYIL VFLLCGVGVF FMFKLKFIQI TKLKQSFVAT FGGLKFGKKA
ETGKMNSFQA LATAISAQVG TGCLAGTATA LIMGGPGAIF WMWVSGFLGM GTIFAEATLA
QEYRSEINGQ MVGGPAYYIK KGLKNKYLAG FFAGAMCLSS LFTGNAVQSN AIGTAFKASF
GINPYIMGAI LVVLALMILL GGMSRIGSFA EKVVPIMAGI FVVGSVFIIG ANYKNIWPAF
QLIFKGAFSP DAVVGATAGV IIKNAMRYGM ARGLFSNEAG MGSTPHAHAV ADVKHPCQQG
LVAMMGVFID NFIILTLTAM VIMTTISPAM FSDYKGIDLT QAAFTVGMGG FGGKFVAISL
FFFAFSTIIG WYFFGETNVK YLFGKKGVVP FQAIFLTCTM IGCALRVDLV WAMADLCNGL
MVLPNILALF ALSNIVKKKL EEYSQLDVTS KIKTVNK
//
