ID A0A1M6QAT3_9FIRM Unreviewed; 645 AA.
AC A0A1M6QAT3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein {ECO:0000313|EMBL:SHK17404.1};
GN ORFNames=SAMN02745123_00936 {ECO:0000313|EMBL:SHK17404.1};
OS Desulforamulus aeronauticus DSM 10349.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC Desulforamulus.
OX NCBI_TaxID=1121421 {ECO:0000313|EMBL:SHK17404.1, ECO:0000313|Proteomes:UP000183997};
RN [1] {ECO:0000313|EMBL:SHK17404.1, ECO:0000313|Proteomes:UP000183997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10349 {ECO:0000313|EMBL:SHK17404.1,
RC ECO:0000313|Proteomes:UP000183997};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
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DR EMBL; FRAR01000008; SHK17404.1; -; Genomic_DNA.
DR RefSeq; WP_072911304.1; NZ_FRAR01000008.1.
DR AlphaFoldDB; A0A1M6QAT3; -.
DR STRING; 1121421.SAMN02745123_00936; -.
DR OrthoDB; 9761899at2; -.
DR Proteomes; UP000183997; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR CDD; cd02980; TRX_Fd_family; 1.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 2.
DR Gene3D; 6.10.250.1450; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01257; 2Fe-2S_thioredx; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR Pfam; PF10531; SLBB; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 566..595
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 596..625
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 645 AA; 70291 MW; 3073838267AF75A5 CRC64;
MRIKGLQDLE LIKKKHLPNL NARLGNNQTA GYQVLCCTGT GCSSGGSEKV IKTLNNQIKQ
HDLQNKVTVY KTGCFGFCKM GPILLVHPGQ IFYCLVHEKD AEEIVSEHFS KGNIVERLLY
KEPIENKIYP QLKDIPFFQA QQRIALRNCG LIDPEEIEEY IANDGYFALQ NVLHNLTPPG
VIEIMAQSGL RGRGGGGFPV GRKWSFTAQA EDSPKYVVCN ADEGDPGAFM DRSILEGDPH
SVLEAMTIAG YSTGASQGVI YVRAEYPIAI KRLELAIKQA HQMGLLGENI FDSDFSFSIE
LRLGAGAFVC GEETALLKSA MGQRGEPRPR PPFPAVCGFR NKPTLINNVE TYANVPIILR
KGAAWYASLG TEKSKGTKVF SIAGKINNTG LIEVPMGTTL RTIIYDIGGG IPGGKKFKAV
QTGGPSGGVI PAQLLDTTID YESLSKIGSM MGSGGLIVMD ETDCMVDIAK FYLGFSQDES
CGKCTPCRVG TKRMLEIMER ITQGKGEMAD LDELEELARD IQETSLCGLG QHAPNPVLST
LHYFRDEYLA HVQDKRCPAG VCQELTDFVV NPEKCIACGI CAKACATQAI IGEKKKNYYI
DRQKCSKCGV CQTRCPKDAI FKAAMGGDNA SAYQPGNNHT TYPTP
//
