ID   A0A1M6RHG2_9CLOT        Unreviewed;       987 AA.
AC   A0A1M6RHG2;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=type I site-specific deoxyribonuclease {ECO:0000256|ARBA:ARBA00012654};
DE            EC=3.1.21.3 {ECO:0000256|ARBA:ARBA00012654};
GN   ORFNames=SAMN02745883_01797 {ECO:0000313|EMBL:SHK31864.1};
OS   Caminicella sporogenes DSM 14501.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Caminicella.
OX   NCBI_TaxID=1121266 {ECO:0000313|EMBL:SHK31864.1, ECO:0000313|Proteomes:UP000184082};
RN   [1] {ECO:0000313|EMBL:SHK31864.1, ECO:0000313|Proteomes:UP000184082}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14501 {ECO:0000313|EMBL:SHK31864.1,
RC   ECO:0000313|Proteomes:UP000184082};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endonucleolytic cleavage of DNA to give random double-stranded
CC         fragments with terminal 5'-phosphates, ATP is simultaneously
CC         hydrolyzed.; EC=3.1.21.3; Evidence={ECO:0000256|ARBA:ARBA00000851};
CC   -!- SIMILARITY: Belongs to the HsdR family.
CC       {ECO:0000256|ARBA:ARBA00008598}.
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DR   EMBL; FRAJ01000014; SHK31864.1; -; Genomic_DNA.
DR   RefSeq; WP_072967744.1; NZ_FRAJ01000014.1.
DR   AlphaFoldDB; A0A1M6RHG2; -.
DR   STRING; 1121266.SAMN02745883_01797; -.
DR   Proteomes; UP000184082; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009035; F:type I site-specific deoxyribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1570.50; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR007409; Restrct_endonuc_type1_HsdR_N.
DR   InterPro; IPR040980; SWI2_SNF2.
DR   PANTHER; PTHR42927; HELICASE SUPERFAMILY 1 AND 2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR42927:SF1; HELICASE SUPERFAMILY 1 AND 2 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF04313; HSDR_N; 1.
DR   Pfam; PF18766; SWI2_SNF2; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184082};
KW   Restriction system {ECO:0000256|ARBA:ARBA00022747}.
FT   DOMAIN          288..481
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
SQ   SEQUENCE   987 AA;  112959 MW;  E974582EC5D10DA7 CRC64;
     MPTNTKESGL EALIVNYLVN KNGFEQGTNE DYNRDYAVDE TRLFRFLQET QPDEVEKIGI
     LNSQHKKEQF LNRLQGEIAK RGIIDVLRKG ISFYPVNLIM FYMTPSEKNI KAKEMFEKNI
     FSVTRQLMYS KNNTQLAIDL AIFINGLPII TCELKNRLTK QNVEDAVQQY KLDRDPRELL
     FQFKRCMVHF AVDDNEVKFC TRLEGKKSWF LPFNKGYNGG AGNPPNPNGI KTDYLWKEIL
     TKNELANIIE NYAQVVAEED EYTKKKKYKQ IFPRYHQLSV VKALLADVKE KGVGQKYLIQ
     HSAGSGKSNS IAWTAHQLVG FEKDGKNIFD SVIVVTDRVN LDKQIKNTIK QFMQVSSTVG
     HAENSGDLKK LIKEGKKIII TTVQKFPYIL DEIGTEHKGR NFAIIIDEAH SSQSGRMSAK
     MNMALSGEYT NDEEETVEDK IIKMMEGRKM LKNASYFAFT ATPKNKTLEM FGIPVPNGDK
     VQYKPFHIYT MKQAIEEGFI LDVLKYYTPI SSYYKIAKIV EDDPMFDKKK AQKKLKKYVE
     SNSYAIEQKA DIMVTHFHEQ VIAKGKIGGK ARAMVVTSSI ERAIDYYYAI TKCLEKRKSP
     YKAIVAFSGE KEYKGKVLTE ASINGFPSSQ IETEFKKDPY RFLIVANKFQ TGYDEPLLHT
     MYVDKVLSGI KAVQTLSRLN RAYPGKTDTF VLDFANDTDT IKKAFETYYT TTILSEETDP
     NKLYDLVTEM EQHQVYTDYH VNTLVELYLS GADRDRLDPI LDACVGIYEN LEEDEQVSFK
     SSAKAFVRTY SFLGAILPYG NAEWEKLALF LNLLIPKLPS PVEEDLSKGI LDAIDLDSYR
     AEIKQTMSII LEDQTEYSVG PVPTKSGGGI NEPEMDLLSN ILESFHDMWG NIDWKDEDQV
     KRHIASIPAV VSKDVAYQNA MKNSDKQNAR IESERALNRA MINMMADNME LFKQFNDNPS
     FKKWLSDMVF NLTYNTKGEV YTGEINI
//