ID   A0A1M6T8I2_9FIRM        Unreviewed;       928 AA.
AC   A0A1M6T8I2;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=NlpC/P60 family protein {ECO:0000313|EMBL:SHK53285.1};
GN   ORFNames=SAMN02745243_03161 {ECO:0000313|EMBL:SHK53285.1};
OS   Hespellia stercorisuis DSM 15480.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Hespellia.
OX   NCBI_TaxID=1121950 {ECO:0000313|EMBL:SHK53285.1, ECO:0000313|Proteomes:UP000184301};
RN   [1] {ECO:0000313|EMBL:SHK53285.1, ECO:0000313|Proteomes:UP000184301}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15480 {ECO:0000313|EMBL:SHK53285.1,
RC   ECO:0000313|Proteomes:UP000184301};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase C40 family.
CC       {ECO:0000256|ARBA:ARBA00007074}.
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DR   EMBL; FQZY01000056; SHK53285.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1M6T8I2; -.
DR   STRING; 1121950.SAMN02745243_03161; -.
DR   Proteomes; UP000184301; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd14667; 3D_containing_proteins; 1.
DR   CDD; cd12797; M23_peptidase; 1.
DR   Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR   Gene3D; 2.70.70.10; Glucose Permease (Domain IIA); 1.
DR   InterPro; IPR011055; Dup_hybrid_motif.
DR   InterPro; IPR000064; NLP_P60_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR016047; Peptidase_M23.
DR   PANTHER; PTHR21666:SF270; OUTER MEMBRANE ANTIGENIC LIPOPROTEIN B; 1.
DR   PANTHER; PTHR21666; PEPTIDASE-RELATED; 1.
DR   Pfam; PF00877; NLPC_P60; 1.
DR   Pfam; PF01551; Peptidase_M23; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   SUPFAM; SSF51261; Duplicated hybrid motif; 1.
DR   PROSITE; PS51935; NLPC_P60; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184301};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        371..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          805..928
FT                   /note="NlpC/P60"
FT                   /evidence="ECO:0000259|PROSITE:PS51935"
FT   REGION          1..238
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..26
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        42..70
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        71..88
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        89..142
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        183..204
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        211..238
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   928 AA;  103420 MW;  18AFD324BE8F8BD9 CRC64;
     MAEQRMKVRD KKVQKMTKDG LVEENLTEKS SVRVSSRASD VQMGKKGKDD FNLSDKPPVK
     ADKRGKNVRS SVQNSRDAPA TARAEQQTAQ ESRKQRNQRM VRRESGKVAR EKENSTTESG
     RLKEKQVELS QSRGDSRRKQ NGGSKKPKQK QRLQFAYEET GASVKGEKET EKFNQMDADG
     VNFRKQNQKE RADKLSYEEA KKKTAPKKHS RKEKVYQEHA DENVGKKKSR LKFGSEESDC
     EKKAEVLKKA SGAASAALHR KIRKNEDDNA AVEGTHKLEE GAEGAYRLKQ KSARWRKQWT
     ARKRSSLERQ AAQKQEQKKL KKLIQKQRIK RDYAKAKHSE QAAGTAAKGT IDYIKKIGGK
     VTNFFKENRK VYISVAVLIG LMMLIMTNVT SCSSLFLQNL ITYTGTSYLS SDEAIREAEL
     YYTQLEANLQ ERINNMESEE PGHEEYRYNI GPIEHDPFVL ISYLSAKYEE FTFEQVKPEL
     DALFALQYHL ETEAVNETVT ETTTVRVGES LGQVVTSGYC NCPICCGIWS GGPTASGAYP
     TASHTLAVDA SDPFVPMGTK VVMNGVEYTV EDTGAFARYG VQFDVYYDNH AAASAHGHQT
     WECYLADDNG SQEVEVTRTR KVDVLNVTLN SGNLMAICQD RLGFFQKELF SAYNDTKGNL
     QMFATPVEFN WYSSVTSYYG YRIHPISGAN QLHNGMDIGA PEGSKVMAGL TGTVVTSAYN
     DSYGNYVVIK DSKGYELRYA HLSSRIVSAG SAVTKGDEIG LVGSTGNSTG SHLHIELLKN
     GERLNPIFYL ETGEGSIFGG NEYTSEAAQR LLEEAARYLG TPYVWGGYSP SGFDCSGFVS
     YCLTNSGVRN TGRLTAQGLY DICTPVSQSD AQPGDLIFFT GTYDAGVPVT HIGIYVGNGQ
     MIHCGHPVQY TSINSPYWQS HFYGFGRW
//