ID   A0A1M6TAD4_9BACL        Unreviewed;       386 AA.
AC   A0A1M6TAD4;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE            EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN   ORFNames=SAMN05443507_11614 {ECO:0000313|EMBL:SHK54012.1};
OS   Alicyclobacillus montanus.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Alicyclobacillaceae;
OC   Alicyclobacillus.
OX   NCBI_TaxID=1830138 {ECO:0000313|EMBL:SHK54012.1, ECO:0000313|Proteomes:UP000184016};
RN   [1] {ECO:0000313|Proteomes:UP000184016}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USBA-503 {ECO:0000313|Proteomes:UP000184016};
RA   Varghese N., Submissions S.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC         mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC         ChEBI:CHEBI:68623; EC=5.1.3.14;
CC         Evidence={ECO:0000256|ARBA:ARBA00036080};
CC   -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC       {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
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DR   EMBL; FRAF01000016; SHK54012.1; -; Genomic_DNA.
DR   RefSeq; WP_072874432.1; NZ_FRAF01000016.1.
DR   AlphaFoldDB; A0A1M6TAD4; -.
DR   STRING; 1830138.SAMN05443507_11614; -.
DR   Proteomes; UP000184016; Unassembled WGS sequence.
DR   GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR   CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR   InterPro; IPR029767; WecB-like.
DR   NCBIfam; TIGR00236; wecB; 1.
DR   PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR   PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR   Pfam; PF02350; Epimerase_2; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184016}.
FT   DOMAIN          24..364
FT                   /note="UDP-N-acetylglucosamine 2-epimerase"
FT                   /evidence="ECO:0000259|Pfam:PF02350"
SQ   SEQUENCE   386 AA;  43312 MW;  9F27DBCBA86A4000 CRC64;
     MEKIRVMTVF GTRPEAVKMA PLVKALESEP LVESIVCVTA QHREMLDQVL NVFAVEPDDD
     LDIMEPQQTL GTITRKALEG IEQVIAKRRP HIVLVHGDTT TTFAAALAAF YQQVAIGHVE
     AGLRTYDKYS PFPEEMNRQL ADVLSDLFFA PTDLAAEQLR REGKPDEAIY VTGNTAIDAM
     KTTVYSTYRH PILEQLPPHS QLVYMTSHRR ENLGEPLRNI CSAVLRLVES HTDVQLIYPV
     HLNPSVRDTV FTMLGGHPRI HLIDPLGIVD NHNFMARAKL ILTDSGGIQE EAPSLGIPVL
     VLRDTTERPE GIEAGTLKLV GTNEKEIYET ASRLLTDQEF YKDMAGRKNP YGDGKASERI
     VEAILHYFGH RDRPKAFVYN ENHEQA
//