ID A0A1M6TMG2_9CLOT Unreviewed; 445 AA.
AC A0A1M6TMG2;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Radical SAM core domain-containing protein {ECO:0000259|PROSITE:PS51918};
GN ORFNames=SAMN02745912_03730 {ECO:0000313|EMBL:SHK57978.1};
OS Paramaledivibacter caminithermalis DSM 15212.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Paramaledivibacter.
OX NCBI_TaxID=1121301 {ECO:0000313|EMBL:SHK57978.1, ECO:0000313|Proteomes:UP000184465};
RN [1] {ECO:0000313|EMBL:SHK57978.1, ECO:0000313|Proteomes:UP000184465}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15212 {ECO:0000313|EMBL:SHK57978.1,
RC ECO:0000313|Proteomes:UP000184465};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the radical SAM superfamily. Anaerobic
CC sulfatase-maturating enzyme family. {ECO:0000256|ARBA:ARBA00023601}.
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DR EMBL; FRAG01000097; SHK57978.1; -; Genomic_DNA.
DR RefSeq; WP_073153552.1; NZ_FRAG01000097.1.
DR AlphaFoldDB; A0A1M6TMG2; -.
DR STRING; 1121301.SAMN02745912_03730; -.
DR OrthoDB; 9808591at2; -.
DR UniPathway; UPA00782; -.
DR Proteomes; UP000184465; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023867; Sulphatase_maturase_rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR43787:SF3; FEMO COFACTOR BIOSYNTHESIS PROTEIN NIFB; 1.
DR PANTHER; PTHR43787; FEMO COFACTOR BIOSYNTHESIS PROTEIN NIFB-RELATED; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01384; thioether_bond_formation_requi; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000184465};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 87..326
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 445 AA; 51615 MW; 33AA8569A0DA78A8 CRC64;
MLKSSHYNIE ITKDNNNESV IFNSFTGAMA IIDSKTYEYI NNNDFIDISD VPEEIKDNII
LMETHGYLVD KDIDEKERLN ILSNIARFGQ KTLVLTIAPT MDCNMSCPYC YEDHQQSKMS
QKTALKLVEF TKKHLITNRF NSLYIGWYGG EPLLEIKTIS KISRKLIEFC NDNNIRFNSS
IITNGLLLTK DIAKLLKNDC KIGACQITVD GPKDINNKRR ISKDGKDSFT QIINNIDDCK
EDMFISIRVN VDRYNNESMY ELIDFFKSKN DWNERVNYYF APVENLTEAC TYNKKSCFSH
SEFADINANL LRYQYSLSKN MEIPRPKPKH LPCEHISPNV FVVDPKGYLY KCWNNVGIVS
LNVGHVDSGP IFNKEHMKWL SYKIPNECEE CNKRPLCQGG CPYAVMQNDC KLECHHFSMG
FETNLELLKD QFLTNELRNH EKEVK
//
