ID A0A1M6TMI9_9RHOB Unreviewed; 721 AA.
AC A0A1M6TMI9;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Tyrosine-protein kinase Etk/Wzc {ECO:0000313|EMBL:SHK58154.1};
GN ORFNames=SAMN05444000_1422 {ECO:0000313|EMBL:SHK58154.1};
OS Shimia gijangensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae.
OX NCBI_TaxID=1470563 {ECO:0000313|EMBL:SHK58154.1, ECO:0000313|Proteomes:UP000183982};
RN [1] {ECO:0000313|Proteomes:UP000183982}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 100564 {ECO:0000313|Proteomes:UP000183982};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-
CC [protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:46858,
CC ChEBI:CHEBI:82620, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001074};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the etk/wzc family.
CC {ECO:0000256|ARBA:ARBA00008883}.
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DR EMBL; FQZQ01000042; SHK58154.1; -; Genomic_DNA.
DR RefSeq; WP_073257109.1; NZ_FQZQ01000042.1.
DR AlphaFoldDB; A0A1M6TMI9; -.
DR STRING; 1470563.SAMN05444000_1422; -.
DR OrthoDB; 9775724at2; -.
DR Proteomes; UP000183982; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05387; BY-kinase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR025669; AAA_dom.
DR InterPro; IPR032807; GNVR.
DR InterPro; IPR003856; LPS_length_determ_N_term.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005702; Wzc-like_C.
DR NCBIfam; TIGR01007; eps_fam; 1.
DR PANTHER; PTHR32309; TYROSINE-PROTEIN KINASE; 1.
DR PANTHER; PTHR32309:SF13; TYROSINE-PROTEIN KINASE ETK-RELATED; 1.
DR Pfam; PF13614; AAA_31; 1.
DR Pfam; PF13807; GNVR; 1.
DR Pfam; PF02706; Wzz; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SHK58154.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000183982};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Tyrosine-protein kinase {ECO:0000256|ARBA:ARBA00023137}.
FT TRANSMEM 30..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 436..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..103
FT /note="Polysaccharide chain length determinant N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02706"
FT DOMAIN 378..458
FT /note="Tyrosine kinase G-rich"
FT /evidence="ECO:0000259|Pfam:PF13807"
FT DOMAIN 531..661
FT /note="AAA"
FT /evidence="ECO:0000259|Pfam:PF13614"
FT COILED 266..372
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 721 AA; 79241 MW; F9BFFC99EF4C3873 CRC64;
MNSSPSNSNS QFDEEIDLGQ LFLNLWQGKW TILFVTFLVG TLSVFWALNT APTYQADALL
QLEEKAGANP FSGTFEGFGS DPASVTEIEL LKSRLILGQA VAEQNLDWVA IPRQTPLIGY
FVSEFGGLVE LPEFMKPFAQ SGETISLRFL RVPPHLLGTP LSLTKISETD FSLKIPEGPT
LSGKLNQQLI DENTGIAIEL SKLEGQVGRE FTVVQESEEE AIKSVREKIG ISEKGRNSGV
LNVTFKDGNK EDASRALNAI VSAYLRQNIS RNSAEAENSL KFIEDRLPEV RSIVDRAEEK
LKDLQSERNT LDLSFETQAL LEQRNQVEAE LAALEIEEQE LQRKYTVSHP NYKMLLSRKE
QLETRLKALE ARSLDLPDTQ REIFDMTQEL ELARETYSKL LIRAQELRVV KASTIGNARV
IDHAQTASLP IAPRKAVIVA LGALLGLMLG VAIVLLKNFR SKGIKSSAEI EALGLSVFAV
VNAVKPGLLK PRKSGGKNPI LAIDDPTDLA VEALRGLRTS LHFGMLEKDA KVLSITSPSP
NAGKSFCSTN LAIVSAQAGQ KVCLIDADLR RGELRKFFGV KKDTPGLAEL LVGDKKSEDV
VTSTSVNTLS FIPTGKFPPN PADLLMTPTF ASTLDKLSEQ FDLIILDCPP VLAVTDPVMI
SKQASMTLVV VRYGVTTEKE MHAMQREIDA SSGTISGAIF NGFQRGKGEK YGGYDYRYEY
K
//
