ID A0A1M6U958_9CLOT Unreviewed; 431 AA.
AC A0A1M6U958;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Serine protease Do {ECO:0000313|EMBL:SHK65706.1};
GN ORFNames=SAMN02745163_04218 {ECO:0000313|EMBL:SHK65706.1};
OS Clostridium cavendishii DSM 21758.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1121302 {ECO:0000313|EMBL:SHK65706.1, ECO:0000313|Proteomes:UP000184310};
RN [1] {ECO:0000313|EMBL:SHK65706.1, ECO:0000313|Proteomes:UP000184310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21758 {ECO:0000313|EMBL:SHK65706.1,
RC ECO:0000313|Proteomes:UP000184310};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S1C family.
CC {ECO:0000256|ARBA:ARBA00010541}.
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DR EMBL; FQZB01000022; SHK65706.1; -; Genomic_DNA.
DR RefSeq; WP_072993034.1; NZ_FQZB01000022.1.
DR AlphaFoldDB; A0A1M6U958; -.
DR STRING; 1121302.SAMN02745163_04218; -.
DR OrthoDB; 9758917at2; -.
DR Proteomes; UP000184310; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR PANTHER; PTHR22939:SF129; SERINE PROTEASE HTRA2, MITOCHONDRIAL; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:SHK65706.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000184310};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 73..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 324..420
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
SQ SEQUENCE 431 AA; 45972 MW; F89615A8B5FDBA95 CRC64;
MDNINNNDVN NKGEFSDYFG MNTSSNTDYK SDDFNNETVK DVNYETVDNK NNKDSKQDKY
KKVNIKNKKG GKIAALIAGA LVCAMLGGAV GATGVYLFAK DNNSSVGTAK KNITYDPPTF
VSSTSKDGVL SATDAVKKIS PAVVGVSVKS IVGRDLFNNT QEQDGIGSGF IINEEGYIVT
NYHVIKGAQE VKAILKDGKE VNAKVINYDA DQDIAVIKIT DNIKVPGVAV LGDSDAIQAG
EDVIAMGNPL GKEFSQTVTK GVVSSANRVV KSESGADIHY IQTDTAINPG NSGGPLINSK
GEVVGINAAK KVGSGIEGIG FSIPINEVKG RLGVLSKPLL KMGIGIKDID ANIAKQYDLE
EGIYISEVSN FSAAEKAGLK RGDVIIKFDG KRIKTSKELN DLKEKHKEGD VVNMVVVRDN
KEVNIQIKLQ S
//
