ID   A0A1M6V487_9BACT        Unreviewed;       906 AA.
AC   A0A1M6V487;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE            EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN   ORFNames=SAMN05720468_106108 {ECO:0000313|EMBL:SHK76126.1};
OS   Fibrobacter sp. UWEL.
OC   Bacteria; Fibrobacterota; Fibrobacteria; Fibrobacterales; Fibrobacteraceae;
OC   Fibrobacter.
OX   NCBI_TaxID=1896209 {ECO:0000313|EMBL:SHK76126.1, ECO:0000313|Proteomes:UP000184030};
RN   [1] {ECO:0000313|EMBL:SHK76126.1, ECO:0000313|Proteomes:UP000184030}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UWEL {ECO:0000313|EMBL:SHK76126.1,
RC   ECO:0000313|Proteomes:UP000184030};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|ARBA:ARBA00001665};
CC   -!- SIMILARITY: Belongs to the helicase family. DinG subfamily.
CC       {ECO:0000256|ARBA:ARBA00038058}.
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DR   EMBL; FRBE01000006; SHK76126.1; -; Genomic_DNA.
DR   RefSeq; WP_073226876.1; NZ_FRBE01000006.1.
DR   AlphaFoldDB; A0A1M6V487; -.
DR   STRING; 1896209.SAMN05720468_106108; -.
DR   OrthoDB; 9803913at2; -.
DR   Proteomes; UP000184030; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProt.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   CDD; cd06127; DEDDh; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR006555; ATP-dep_Helicase_C.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR045028; DinG/Rad3-like.
DR   InterPro; IPR006054; DnaQ.
DR   InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR   InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   NCBIfam; TIGR00573; dnaq; 1.
DR   PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR   PANTHER; PTHR11472:SF47; FANCONI ANEMIA GROUP J PROTEIN; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF13307; Helicase_C_2; 1.
DR   Pfam; PF00929; RNase_T; 1.
DR   SMART; SM00479; EXOIII; 1.
DR   SMART; SM00491; HELICc2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:SHK76126.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184030}.
FT   DOMAIN          235..511
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51193"
SQ   SEQUENCE   906 AA;  101037 MW;  CFE2418CCAB53F44 CRC64;
     MEMISSFVAI DLETTGLDFE KDEIIEVALV RFENGEPVES VDYLVKPSTA VLRPFIENLT
     GISNADLETA ETFGALAGKI YNFIGDLPIV AHNANFDSKF LKQTFQKVGV SFENHVVWDS
     LTVSRIAYQN IPNHRLDTLV QELNIPRSRA HRALPDADAC GRLFVMSIQK IAASDEWLLN
     ALGRIAVESQ WASLWPAVDG VQNEPNYSFP VVPQETILSK DRAPRVSEFF KEDGLLSKAV
     EKFQVRPNQQ DLASAVERNM HKGGLCVVEA PTGSGKSMAY LVSAANKAVS GERVVISTAT
     RALQEQLWNH DIPMIAGLYQ DKLKPAVLKG RENYLCIRKF EELLAAPNML LLPEERDSFM
     AIVPWVYTST TGDVNECTSF SQGRNRVLWS KMASSAKSCL GEKCSHYAHC PALAAKRKAM
     NSNLLLVNHS LFLSDMSLDF ALLPLYEHIV FDEAHRLPEI SNQSLGRTVS FFGLRNAMKT
     VLPSRNRQDG LLVEIASQIP AEETELHEAC ANLSESLSET EKCLHRFFMK IGKKLTKQKN
     GKNGFVYTSG IAAEYDADPS AFLDQCQKSM KIADKLFEDV KNLKNENLAG LVSDLSGRMT
     ELSRFVSDFE FLTKASREGW VFFMEEPFNP HTIKLHAYPL NSGSVWKEKF YPWIKSATFV
     SATLAVQGDL GYYVQKMGMD SLEGSKRPFL RVYNESNSKN ERQSVMVVKY LPKPSAPEYN
     DGVNETLASV LPDVSENTMV LFTSISAMLK AQAALAPLFA QKNKLLLCQN VDGSLDGLVA
     MFRRERGACL LGCQSLWEGV DFPGDALKLL VIPKLPFPNP MDPLVAGISA KMKDEGKNAF
     KDYFVPEAYM ELRQGLGRLI RSDEDTGKVL ILDNRVVLEA YGKSFSKIWN MKQKVASNLD
     DIKSFL
//