ID   A0A1M6V7W5_9FIRM        Unreviewed;       465 AA.
AC   A0A1M6V7W5;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Glycoside/pentoside/hexuronide:cation symporter, GPH family {ECO:0000313|EMBL:SHK77572.1};
GN   ORFNames=SAMN02745243_03708 {ECO:0000313|EMBL:SHK77572.1};
OS   Hespellia stercorisuis DSM 15480.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Hespellia.
OX   NCBI_TaxID=1121950 {ECO:0000313|EMBL:SHK77572.1, ECO:0000313|Proteomes:UP000184301};
RN   [1] {ECO:0000313|EMBL:SHK77572.1, ECO:0000313|Proteomes:UP000184301}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15480 {ECO:0000313|EMBL:SHK77572.1,
RC   ECO:0000313|Proteomes:UP000184301};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC   -!- SIMILARITY: Belongs to the sodium:galactoside symporter (TC 2.A.2)
CC       family. {ECO:0000256|ARBA:ARBA00009617}.
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DR   EMBL; FQZY01000085; SHK77572.1; -; Genomic_DNA.
DR   RefSeq; WP_073113003.1; NZ_FQZY01000085.1.
DR   AlphaFoldDB; A0A1M6V7W5; -.
DR   STRING; 1121950.SAMN02745243_03708; -.
DR   OrthoDB; 9764596at2; -.
DR   Proteomes; UP000184301; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   CDD; cd17332; MFS_MelB_like; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR039672; MFS_2.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR001927; Na/Gal_symport.
DR   NCBIfam; TIGR00792; gph; 1.
DR   PANTHER; PTHR11328:SF24; INNER MEMBRANE SYMPORTER YICJ-RELATED; 1.
DR   PANTHER; PTHR11328; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13347; MFS_2; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184301};
KW   Symport {ECO:0000256|ARBA:ARBA00022847};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022847}.
FT   TRANSMEM        20..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        43..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        83..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        111..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        153..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        239..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        277..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        318..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        419..438
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   465 AA;  51202 MW;  9916BEC8DC68439B CRC64;
     MEEKKYLKWY NKIGYGSGDI AGNVVYAFLT SFMMVYLTDS VGLAAGVVGT LIAVSKLFDG
     FTDIFFGSMI DKTHSKMGKA KPWMLYGYIG CAITLVCCFA VPVSWGTTAK YAWFFISYTL
     LNGVFYTANN IAYSALTSLI TKNSKERVQM GSYRFIFAFS TSLLIQAITV GFVDKCGGDA
     AAWRTVAIIY AIIGLIVNTI SALSVKELPE EELNEGETKN KDEKYGMVQA FKLLIKNKYY
     MMICGTYILQ QLYSAMIGAG IYYMTWVLKN KNLFGQFAWA VNIPLIIALI FTPTLVGKWK
     GMYKLNLRGY MLAVVGRALV VVAGYMGSVP LMMAFTALAA LGQGPWQGDM NAVIASCSEY
     TYLTQGKRID GTMYSCTSLG VKIGGGIGTA VVGWMLEFSG YVGTNATQPQ SALNMMQFMY
     LWLPLIFDVL IMFVLSRMNV EGANEKLKAE KGITADEVTD ASDME
//