ID A0A1M6V8X3_9BACT Unreviewed; 479 AA.
AC A0A1M6V8X3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Multidrug-efflux transporter {ECO:0000256|ARBA:ARBA00031636};
GN ORFNames=SAMN05720469_11743 {ECO:0000313|EMBL:SHK77957.1};
OS Fibrobacter intestinalis.
OC Bacteria; Fibrobacterota; Fibrobacteria; Fibrobacterales; Fibrobacteraceae;
OC Fibrobacter.
OX NCBI_TaxID=28122 {ECO:0000313|EMBL:SHK77957.1, ECO:0000313|Proteomes:UP000184275};
RN [1] {ECO:0000313|Proteomes:UP000184275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UWOS {ECO:0000313|Proteomes:UP000184275};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FRAW01000017; SHK77957.1; -; Genomic_DNA.
DR RefSeq; WP_073304666.1; NZ_FRAW01000017.1.
DR AlphaFoldDB; A0A1M6V8X3; -.
DR Proteomes; UP000184275; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR CDD; cd13133; MATE_like_7; 1.
DR InterPro; IPR002528; MATE_fam.
DR InterPro; IPR048279; MdtK-like.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR43298:SF2; FMN_FAD EXPORTER YEEO-RELATED; 1.
DR PANTHER; PTHR43298; MULTIDRUG RESISTANCE PROTEIN NORM-RELATED; 1.
DR Pfam; PF01554; MatE; 2.
DR PIRSF; PIRSF006603; DinF; 1.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 442..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 479 AA; 52585 MW; B46A16D0697C32E2 CRC64;
MIADVASKFP FAKMLKISKM KKNGDIKDVL IVALPMILSM SFDTLMTFVD RLFLSKLGPT
EMNASLGGGG MSVVLLTFFT GTLSYTTAMV AQRLGARKNA DCSKIFIQAV YLSVFCLPFL
FLTIPLGHWV FRMQNLDAAQ FSAQTTYFDI LMYGGIINLV RNAAPCFFTG IGETKIVMKA
AFVGMITNVV CNYFLIYGFG PIPCFGVAGA AYGTLFGNFV STAILLGAYF GKRYRRRFLT
TSSFALNGRL IRELLSRGLP AGVEMFLNMS AFQLLILMLH GLGPVSATSA SIMFNWDMVA
YVPLLGLEIA TTSLVGRYAG AKAGAAANRS TFSGLKIGWM YSLFIGILFL FLPGVLADVF
SPENSASAEA LAVFAEARPH AIFMVRFATI YIIVEVLMVV YAGALRGAGD TIWVMCMSGI
MNWTAAIALY LAAYVLNLPS HFAWIVVIAS YGIAPLFYWR RWKSGRWRRH VMDADRRVA
//
